Hey everyone, I was wondering if anyone here with any or all of these SNPs (A1298c homozygous /A1298c C677t compound heterozygous; homo or hetero ACAT; ACE; ANCY; BHMT; CBS; COMT; MAO A; MTR/MTRR; NOS; SHMT; SUOX; VDR taq), Hashimoto's (or simply hypothyroid) and AF, takes l-tyrosine with any success. It is something I, as someone with Hashimoto's, AF and seemingly likely above mutations (going by symptoms alone, mind; I am waiting on a test kit from Dr. Yasko) should consider taking in the future? If so, at what stage in the treatment protocol - i.e. is it unsafe to start taking them beforecompleting Yasko's protocol of SHMT/ACAT, CBS, MTHFR, MTR /MTRR, BHMT, MAO A, SUOX, NOS, VDR? Dr Ben says, in response to two questions: "MTHFR is related to thyroid disorders because of BH4. Methylfolate is needed to produce biopterin which is needed to convert tyrosine into active neurotransmitters and thyroid hormones...." "Since dopamine supports speech, it makes sense that MTHFR 1298 may be an issue here as her methylfolate levels are likely low thereby causing a deficiency of BH4 which in turn limits conversion of tyrosine to dopamine." Obviously I am not going to start taking them before my results arrive, which I estimate will take around 3 months, but I am simply wondering what anyone else thinks.