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A study looking into energy status & MRS in CFS

Discussion in 'Active Clinical Studies' started by Dolphin, Jan 25, 2017.

  1. Dolphin

    Dolphin Senior Member

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    From Twitter:










    Anyone have the image or a link to further information?
     
  2. Sasha

    Sasha Fine, thank you

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    UK
    https://www.psych.ox.ac.uk/team/beata-godlewska
     
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  3. Sidereal

    Sidereal Senior Member

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    More neuroimaging? :confused:
     
  4. Snow Leopard

    Snow Leopard Hibernating

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    Yeah, neuroimaging just doesn't turn me on either.

    I mean, you measure some differences, then what? I mean how does it lead to treatments? I just don't understand.
     
  5. Esther12

    Esther12 Senior Member

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    I don't think I'd support any funding going to a UK psychiatrist for ME/CFS research unless they've already spoken out about the PACE trial.
     
  6. Tom Kindlon

    Tom Kindlon Senior Member

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    Oxford study that is recruiting.jpg
     
  7. charles shepherd

    charles shepherd Senior Member

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    This is all quite interesting.........

    However, can I point out that this neuroimaging study at Oxford is NOT part of the MEA RRF funded research studies that are taking place at Oxford

    I do not know the doctor involved and have not had any contact with her

    And I was not even aware of this 'energy status' research until the info appeared here on PR!

    The study sounds interesting and I will try find out more about it……...

    CS
     
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  8. FMMM1

    FMMM1 Senior Member

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    Check out the article on Cort Johnson re this 2017 paper "Elevations of ventricular lactate levels occur in both chronic fatigue syndrome and fibromyalgia - C. Shungu".

    Basically they measured the concentration of lactate and glutathione (antioxidant) in cerebrospinal fluid using MRS (magnetic resonance spectroscopy).

    To me the study confirms what the seahorse/nano needle showed i.e. metabolic problems with a switch to anaerobic energy production.

    In the article they suggest that increasing glutathione and using a non steroidal anti-inflammatory may be a potential treatment.

    This is from Wikipedia: "Acquiring an MRS scan is very similar to that of MRI with a few additional steps preceding data acquisition". Therefore, if MRS is useful then presumably the MRI's could be used for MRS.



    MRS measures the concentration of lactate and glutathione in the cerebrospinal fluid; it is not an imaging technique. Interestingly MRIs are based on the same technique
     

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