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A report about anti-glycation supps Carnosine Beta-Alanine (=methylation?)

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Gondwanaland, Mar 31, 2017.

  1. Lolinda

    Lolinda after meals, I need to lay in bed for hours

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    Just stumbled across this - I am surprised what glycation can do:

    https://paleoleap.com/paleo-bones-joints/
    In this study, for example, women with Type 2 diabetes had higher bone mineral density at the neck, but “weaker skeletal geometry:” in real-life situations, their bones didn’t hold up as well to stress.
    Some studies have suggested that this effect might be caused by advanced glycation end-products
     
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  2. NotThisGuy

    NotThisGuy Senior Member

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    Germany
    Thats horrible.
    Your amalgam fillings explain why you never tried ALA.
    There is a guy in the yahoo chelation group with high aluminum, it went down the further he progressed mercury chelation.

    BTW: here is what cutler is saying about carnosine and chelation:

    http://onibasu.com/archives/am/120163.html

    In short: he thinks it's not a chelator.


    But who knows....
     
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  3. Gondwanaland

    Gondwanaland Senior Member

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    Aluminum is easy to get dow with malic acid and/or silica. I have eliminated all aluminum sources in my kitchen long ago - the last one was the moka coffee pot which has been replaced by a glass French press a couple of years ago.

    It might not be, but it activates an inner chelation system probably by skyrocketing glutathione, raising thyroid metabolism, making anti-oxidant mechanisms more available, and above all stopping glycation which is vastly underestimated in the non-diabetic population.
     
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  4. Gondwanaland

    Gondwanaland Senior Member

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  5. Asklipia

    Asklipia Senior Member

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    Still improving on carcinine and thiamine.
    Interestingly, the only place where I found carcinine for sale outside of Brazil, supersmart.eu, sell an antiglycation formula which associates:
    L-carnosine 1000 mg
    Benfotiamine 120 mg
    Aminoguanidine 100 mg
    L-histidine 88 mg
    Sodium R-lipoate 80 mg
    Guava leaf extract 4:1 80 mg
    Yerba mate leaf extract 4:1 60 mg
    Pyridoxamine 60 mg
    Banaba leaf extract (1% corosolic acid) 10 mg
    Other ingredients : Microcrystalline cellulose, magnesium stearate, silicon dioxide

    So it seems thiamine and carcinine are complementing each other.
     
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  6. Gondwanaland

    Gondwanaland Senior Member

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    This must explain my crazy cravings for guava fruit, I was in luck they were in season during my experiment...
    I think that just like Alpha Lipoic Acid, the way carcinine/carnosine works is by activating B1 o_O ( @Lolinda )
    If you look up the supplement Lipothiamine, you will see that it contains ALA

    The formula you posted contains carnosine, if it were carcinine a much lower amount would do the job...
     
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  7. Asklipia

    Asklipia Senior Member

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    How is that?
    I notice that Doctors Best has a benfotiamine + ALA.
     
  8. Gondwanaland

    Gondwanaland Senior Member

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    I haven't looked it up yet
     
  9. Asklipia

    Asklipia Senior Member

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    I was prescribed ALA in 2005. After 3 days of bliss, feeling NORMAL, I crashed abominably. Now if that ALA had used up my last thiamine resources, it would be an explanation.
    These days the past is catching up with me. Lots of unexplained events are finding an explanation, even pertaining to my grand-parents. Very strange. Karma lifting away.
    Be well!
    :hug:
     
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  10. Gondwanaland

    Gondwanaland Senior Member

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    It sounds like my MB12 experience, and I kept thinking for a long time that MB12 would be the solution.
    Feel free to share some eyebrow-raising bits if you wish :woot:
     
  11. Eastman

    Eastman Senior Member

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    Are you thinking mB12 used up your thiamine?
     
  12. Asklipia

    Asklipia Senior Member

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    Could have. I did not take a lot of MB12, after a couple of weeks I crashed slowly :devil::devil::devil:.
    I think I understand now why I was Thiamin Deficient. It was a family thing.

    I never thought B12 was the solution, because I think if you have more B12 you will need more folate (B9). If you have more folate, you cannot absorb B1.
    Catch 22!
     
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  13. Asklipia

    Asklipia Senior Member

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  14. Asklipia

    Asklipia Senior Member

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    No eyebrows yet. Just two tufts of very short but hardy hairs growing at the upper base of the nose. I somehow thought they would have filled up from the temples area, but no, they come from the center. How did yours grow back?
    Also a handful of extra pubes! :rofl:
     
  15. Gondwanaland

    Gondwanaland Senior Member

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    Definetly. It is the only explanation for the crushing fatigue I felt after a short honeymoon with MB12. Adding Mfolate to it was a tragedy.
     
    Last edited: Jul 24, 2017
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  16. Gondwanaland

    Gondwanaland Senior Member

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    :lol:
    No idea, 2 or 3 days on glycoxil and I looked in the mirror and saw my eybrows were already extended towards the temples again... They haven't reached their full original extension nor their full volume, but it is a notable improvement. I will try to put some pictures together.
     
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  17. Asklipia

    Asklipia Senior Member

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    Maybe this did not happen to me because I do not take thyroid meds and I think you do.
    So my thyroid could still improve and there is further hope for my eyebrows?
    I notice that thyroid hormones inhibit thiamin absorption.
     
  18. Gondwanaland

    Gondwanaland Senior Member

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    I do, but most of my thyroid hormones are endogenous since my replacement dose is ridiculously low and obviously I don't tolerate higher dosage for various deficiencies. The 1st evident deficiency when I try to up my dose is B2.
    Please let me know what you find out
    Yes, this is a well-established fact.
     
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  19. Eastman

    Eastman Senior Member

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  20. Asklipia

    Asklipia Senior Member

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    I forgot to say that I take magnesium as per Lonsdale recommendation as magnesium/potassium aspartate.
    Yes I am sure that Folate + B12 deplete Thiamine, 100 % sure from my personal observation.
     
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