Hi All, I think I know what the answer may be (because I've seen it here and there) but is this therapy indicated for those w/low CD 19 cells, since it is a B-cell depleter? My wife & I both have ME/CFS and hers are very low (but not atypical) @ 84. We both got ME/CFS through having mono (EBV). I have seen some here mention the possibility? of Rit. affecting the EBV infecting the B cells. Would someone in my wife's status (low CD19) be at risk of lowering her existing CD 19's or is that not likely?