The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
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A paper on possible effects of Rituximab on Borrelia antibodies

Discussion in 'Lyme Disease and Co-Infections' started by Mel9, Feb 11, 2017.

  1. Mel9

    Mel9 Senior Member

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    Might this paper be relevant for some of those on Rituximab treatment?

    It also shows that people with Borrelia infection (i.e. Lyme disease) can show up negative for antibodies to Borrelia, so it is wise not to trust a 'negative' for antibody testing if you have typical symptoms.

    The authors write:

    "The sensitivity of B burgdorferi serology in erythema migrans varies from 38 to 88% depending upon the duration of the erythema, which may explain why the patient did not have detectable anti-Borrelia antibodies at that time. Rituximab is known to deplete normal B-lymphocytes and this is likely to have hampered further production of antibodies against B burgdorferi not only in serum, but also in CSF.
     
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  2. TiredSam

    TiredSam The wise nematode hibernates

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    Did you forget the link?
     
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  3. Mel9

    Mel9 Senior Member

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    Yes, sorry about that. Just being dopy and posted the paper separately. I will have to work out how to put the two together.
     
  4. Mel9

    Mel9 Senior Member

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    Here it is, I hope.
     

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