Amen. One person's life-restoring remedy can be another's nightmare. I think one of the biggest issues faced here is that treatments have to be done in careful sequence, and not enough is yet known. It is difficult to get thyroid problems back on track, for instance, if the real problem is the adrenals, and if the real problem behind that is within the ANS after years of poor treatment. Add on the stress of being sick while waiting for results, and it snowballs. The largest piece I have seen that we all have in common is that improved sleep has to happen first before anything else can work.