So, for the past couple of years I’ve had issues with my joints and I wondered if I could get peoples' thoughts on this bunch. My GP never really explains what he’s looking for - hence my search for answers. A few of the tests I've had done: HbA1c: 32 mmol/mol A ENA antibody: negative Rheumatoid factor: <15.0 IU/mL (<30.0) C Reactive Protein: 1.3 mg/L (<5) Ds- Dna 15.5 IU/mL: (0-99.9) ANA anti nuclear antibodies Positive Pattern: Speckled, Titre: 160 Pattern: Nucleolar, Titre: 160 My Endocrinlogist has also just done a blood panel for myositis and that came back clear. I did have a bad reaction to methimazole previously (severe muscle aches in shoulders, hips and thighs to the point I couldn't walk.) However, my main symptoms that are joint related are: - Crepitus in my knees and neck. My knees can be heard across the room sometimes and it’s been worse when I’ve been hyperthyroid. - The joints in my fingers and toes randomly feel like they’re not quite aligned and I’ve put one of my finger joints out of place twice doing something really mundane (using a hammer and the handle pressure has forced the joint out of place.) They’re painful but useable and seem to settle by themselves. I’ve never noticed if it’s always the same joints, it seems to vary. - I’ve also had an AC joint injury that led to bursitis and inflammation that spread up my neck and across to my other shoulder. I couldn’t even tolerate the touch of fabric on my skin at times. (An ultrasound guided steroid shot cleared that up.) (These symptoms may come back to pre-existing conditions (lipedema and now lymphedema) and/or my Grave’s Disease. I’m still waiting on a vascular referral to come through regarding the lymphedema because I’ve had uneven swelling on top of the original (bilateral and symmetric) lipedema. My right leg swells more, right to the top of my thigh, although both legs have it. It is non-pitting and most likely not Graves' related pretibial myxedema.) Any thoughts and suggestions would be greatly appreciated.