The 12th Invest in ME Conference, Part 1
OverTheHills presents the first article in a series of three about the recent 12th Invest In ME international Conference (IIMEC12) in London.
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A Comparison of Case Definitions for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome

Discussion in 'Latest ME/CFS Research' started by Dolphin, Jul 20, 2017.

  1. Dolphin

    Dolphin Senior Member

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  2. hixxy

    hixxy Senior Member

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    Australia
    The London criteria eliminates everyone that doesn't have viral onset so of course it's going to be more narrow.
     
  3. Dolphin

    Dolphin Senior Member

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    I find it hard to understand why one type of symptom has to be of at least moderate severity while other types of symptom only have to be of mild severity.

    I'm left wondering whether these thresholds might have been decided after looking at the data.

    Leonard Jason based on past experience uses "of at least moderate severity" when he is operationalising criteria but in this case they said the decision was made by Ellen Goudsmit.

    They are free if they want to use the threshold "all of the time" for the symptoms but Leonard Jason doesn't use this for his other criteria. I remain to be convinced it is the best way to define ME and so am not confident that the data in this study is in any way definitive.

    The authors themselves say:
     
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  4. Dolphin

    Dolphin Senior Member

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    I remain to be convinced that these differences are that reliable and instead could be due to the different thresholds use for the two criteria as I mentioned in the last comment.
     
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  5. Dolphin

    Dolphin Senior Member

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    Some limitations the authors mention:
     

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