I'm Spanish too and I don't trust it. The article mentions that the doctor who says that 4.000 samples are going to be analyzed is Dr.Rivera. I met Dr.Rivera last year and he was disgusting, unpolite and radical. Probably the most radical doctor against a physical cause of CFS I have ever met. He specifically denied to see any of my medical reports and tests, specifically the tilt table test one where I was diagnosed with severe dysautonomia (even describing a cardiac arrest that I suffered at the test) and anything I had taken with me. He specifically said that "we all get old", that "anxiety is difficult to deal with" and recommended me (by written) psychotherapy and relaxation techniques. And I can prove it because I keep his official medical report, and it's a quite valid one because he works for the Spanish National Health System in a very big and important hospital as a Rheumatologist specialized in Fibromyalgia to whom I was referred by another famous CFS/FM doctor in Barcelona, the one receiving all patients from all over Spain in his CFS/FM private clinic. It's interesting to notice how a Rheumatologist can diagnose an anxiety disorder after a 10 minutes interview without having even looked at my medical reports. And even to recommed by written psychotherapies. And I wonder why such behavior is allowed by law when he is not a specialist in psychiatry or psychology. I have difficulties to believe in these guys. For my experience with him and for my experience with the leader of that suppoused big study going on, Dr.Alegre from Barcelona, who had a horrible and unprofessional attitude when I travelled to see him. The most horrible trip of my life for nothing. Completely unprofessional, also rejecting to read or even see my medical reports and tests and loading me with a hundred medications after a ridiculous quick interview. I wish it was true, but rumours say very bad things about them, and, having personally met these two, I suspect that it's not going to be a happy ending investment of our public money and our hopes. All these doctors involved, first of all, have personal economic interests in CFS. They are all doing their own researches in other hypothesis of CFS and they have private practices which are very demanded and give them a lot of money. They charge a lot for the visits and for the reports that people desperately need for the disability recognition (usually useless and dismissed but still required). Why do I have to believe that they are honestly willing to find a cause and a cure for CFS that will end their very profitable businesses? I hope to be wrong. If only the WPI would agree with their protocol that would help, but I can't help being little confident in all this people. And concerning this post: Dr.Alegre has been working in genomics and proteomics as his hypothesis to solve CFS. He told me in person when we met. That would explain why he will be focusing in families. Again, not very likely that his main interest will be to find XMRV if the study has that purpose at all.