I have been trying to get my doc to increase the Valcyte up to 1800mg again becaused of the winter months but he wont budge. Right now I am convinced that it is the HHV6 that is causing many of my CFS symptoms. When I was on the 1800mg dose I felt so much better. I started to feel really debilitated over the summer months of August. It was only by Septemeber did I do any blood test and it showed HHV6a and EBV in my blood. I went on the Valcyte in the first week of Nov and by the time I had my second blood test in the later part of Nov, EBV was 'Not detected' on PCR Qualitative. This I attribute to the Valcyte. HHV6a was still in my blood. It seems to me that HHV6a is becoming a virus that is very underestimated by doctors. Valcyte is supposed to work on the whole family of Herpes viruses but the virus has still persisted in me until today. I am quite sure that viral titers have gone up in the winter months because I feel worse. HHV6a is not an innocuous virus just because it is in 90% of the population. I think that if u are one of those unlucky few that has an immune system that cannot suppress it, it can do alot of damage that doctors are not aware of. Initially i was supposed to be on Valcyte for 3 months, but it looks like I may need to be on it for longer. I have no money to pursue XMRV/MLV, not even to test for it. For me it stops here and I will manage it with what I can. I know that the Herpes family viruses are not the whole story to this jigsaw puzzle of a disease, but that is as far as I will go in terms of looking for a cure. In fact deep down inside, I dont think there is one and it is just something that I will have to manage for the rest of my life.