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8-hydroxy-2' -deoxyguanosine (8-OHdG)

Discussion in 'Post-Exertional Malaise, Fatigue, and Crashes' started by pemone, Jun 7, 2014.

  1. pemone

    pemone Senior Member

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    8-OHdG is thought to be a biomarker of oxidative stress in the body, and has been measured higher in CFS patients. This is a marker that would show if you are producing a lot of free radicals that are not being contained by antioxidants. Since CFS patients generally have poor ability to regenerate NAD+ from NADH, they end up metabolizing NADH in the mitochondria in a way that creates a lot of free radicals.

    Does anyone know a lab in the US that provides this test? What does it cost?

    http://www.ncbi.nlm.nih.gov/pubmed/19412858
     
  2. PDXhausted

    PDXhausted Senior Member

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    NW US
    This is included in Metametrix's organic acids test. You can order the test without a doctor from mymedlab.com.

    Mine was high when I took it. Their recommendation if high is to take vitamins C and E and lipoic acid.
     
  3. pemone

    pemone Senior Member

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    I think Genova has renamed this as the "ION Profile with 40 Amino Acids"
     

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