When I finally did get clinical depression from having ME, I told my gp I had clinical depression and wanted ADs. With great glee, he got out his little Beck Depression Inventory and asked me all the questions on it over the phone, and agreed. I had clinical depression. (I don't understand why no gp had got out the Beck DI before prescribing ADs to me before that!). Anyhow, I'd heard that Citalopram could be easier for PWME to take than Sertraline. Prozac was out, because I'd been on it years before and it only works the first time you take it. The normal starting dose is 20mg. I only took 10mg. I was bouncing off the walls for 6 weeks, with every known side effect and several unknown, before it finally kicked in. I still only take 10mg. The dose of amitriptyline I was given was the same dose as is given to 7 year-olds to help prevent bed-wetting. It put me on another planet; (nothing to do with aliens) I got all dissociated from myself. Out-of-body sort of experiences. I simply couldn't handle the stuff.