Choline on the Brain? A Guide to Choline in Chronic Fatigue Syndrome
http://phoenixrising.me/research-2/the-brain-in-chronic-fatigue-syndrome-mecfs/choline-on-the-brain-a-guide-to-choline-in-chronic-fatigue-syndrome-by-cort-johnson-aug-2005
Discuss the article on the Forums.

28-day Guanidinoacetic Acid Supplementation Improves Clinical Outcomes In Patients With CFS

Discussion in 'Latest ME/CFS Research' started by Dolphin, Sep 13, 2015.

  1. Dolphin

    Dolphin Senior Member

    Messages:
    10,688
    Likes:
    28,225
    http://journals.lww.com/acsm-msse/F...Basic_Science_World_Congress_Poster__.16.aspx

     
    Valentijn and alex3619 like this.
  2. Ema

    Ema Senior Member

    Messages:
    4,391
    Likes:
    6,249
    Midwest USA
    And of course, the bodybuilding community is already on it...

    This article mentions that you have to take it with betaine since it will deplete methyl groups in the liver and cause homocysteine levels to rise over time.

    http://www.bodybuilding.com/fun/glycocyamine.htm
     
  3. Hip

    Hip Senior Member

    Messages:
    9,757
    Likes:
    15,541
    The Wikipedia article for guanidinoacetic acid is here.

    According to this clinical trial of guanidinoacetic acid, this compound is a biochemical precursor of creatine.


    It does not look like it is available as a supplement as yet (this Google query searches for its various synonyms).
     
  4. Ema

    Ema Senior Member

    Messages:
    4,391
    Likes:
    6,249
    Midwest USA
    Hip likes this.
  5. Ema

    Ema Senior Member

    Messages:
    4,391
    Likes:
    6,249
    Midwest USA
  6. SOC

    SOC Senior Member

    Messages:
    7,839
    Likes:
    16,548
    I question whether these are really well-defined CFS patients. It seems more likely that they have found something that might help with generalized fatigue. This is no surprise since body-builders are already onto this supplement.

    I would like to think that this might help with our energy production problems, but I have no confidence at this point that they have demonstrated that it is effective, or even safe, for ME patients with PEM. I hope further research will use a better patient cohort and use a better measure of ME/CFS energy production problems than the MFI-20. A 2-day, even a 1-day, CPET would be good.
     
    Woolie and Valentijn like this.

See more popular forum discussions.

Share This Page