I've been lurking here for a few days, marvelling at the level of understanding that some of you have. I received my 23andme results back a few weeks ago and I have been trying to work out what they mean ever since. I ran my results through GeneticGenie and livewello. By way of some background info I carried out the 23andme test off the back of a just in range (but very low) B12 blood test result, a high off the chart folate test (even though I don't supplement or eat foods fortified with folic acid) and a slightly high out of range homocysteine level. I have Hashimotos disease and my mum has Parkinson's disease and has also had blood clots. My results are as follows: Homozygous: COMT V158M, COMT, H62H, MAO-A R297R Heterozygous: VDR Bsm, VDR Taq, MTHFR c677T, MTHFR 03p39p, MTHFR A1298c, MTR A2756G, MTRR A66G, BHMT 08, CBS A360A, SHMT1 C1420T. All of the others are -/- To be honest, I don't know where to start or where to look for info and wondered if anyone here can help me?