Hi all, I received my 23andme results a few weeks ago and have been trying to learn as much as possible from the message boards. I would love to get some input on my results and see what you all think! (FYI results analyzed via genetic genie and Sterling’s site app.) As far as treatment, I’ve started with SHMT spray (1 week ago) and every few days take one capsule of the Ultimate B Complex in addition to a trace mineral complex supplement (Seeking Health brand). Once things settle down a bit, I will then start with the Iron Related Bacterial Issues supplement … then onto CBS? Also, urine essential element testing showed low levels of: Calcium, Cobalt, Molybdenum, Manganese, Selenium, Copper, and Sulfur. Urine Creatinine was at 932mg/24hr. (range: 600-1900) Methylation - hetero COMT V158M rs4680 AG +/- COMT H62H rs4633 CT +/- VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MTHFR A1298C rs1801131 GT +/- MTHFR A1572G rs17367504 AG +/- SHMT1 C1420T rs1979277 AG +/- MAO-A R297R rs6323 GT +/- BHMT-04 rs617219 AC +/- BHMT-08 rs651852 CT +/- BHMT R239Q rs3733890 AG +/- CBS A13637G rs2851391 CT +/- CBS A360A rs1801181 AG +/- CBS C19150T rs4920037 AG +/- CBS C699T rs234706 AG +/- DAO rs2111902 GT +/- MTHFD1 C105T rs1076991 CT +/- MTHFD1 G1958A rs2236225 AG +/- MTHFD1L rs6922269 AG +/- Methylation - homozygous MTRR A66G rs1801394 GG +/+ MTHFS rs6495446 CC +/+ DAO rs3741775 CC +/+ TCN2 C766G rs1801198 GG +/+ Detox – homozygous (will post hetero if anyone wants to see them) CYP1B1 L432V rs1056836 CC +/+ CYP2C19*17 rs12248560 TT +/+ PON1 Q192R rs662 CC +/+ GSTT1 ABSENT (via genetic genie)?