New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
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23andme Results Are In!!!

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Changexpert, Apr 3, 2015.

  1. Changexpert

    Changexpert Senior Member

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    As expected, I am Mao +/+... ARGH
    It looks like my detox pathway is pretty decent. I have a couple of specific questions.

    1. Are there any supplements I need to watch out for? Is combination of Mao ++, COMT +/-, VDR +/- and CBS360A ++ prone to ammonia build up?
    2. Is mb12 a poison or a treasure for me?
    3. Is taking phosphatidylserine a good idea since I have heterozygous BHMT?
    4. Is there anyway I can find SUOX mutation status?
    5. What other things should I watch out for with my profile?
    6. What can I do about not genotyped data? :confused:

    I would sincerely appreciate anyone's input. @Valentijn as well :angel:
     

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    Last edited: Apr 3, 2015
  2. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

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    USA
    Yep...watch out and make sure your B2 levels are adequate. This will help MAO work. Otherwise, nice genes... Could be much worse.
     
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  3. Valentijn

    Valentijn Senior Member

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    Supposedly you might tolerate hydroxoB12 better than methylB12. But MAOA is a rough guideline at best, and COMT +/- and VDR +/- shouldn't be having any impact.
    Neither: it's a vitamin. It might help a bit with some problems. It's not a cure for anything except B12 deficiency.
    BHMT +/- doesn't have an impact.
    If you sign in at your 23andMe page via https://www.23andme.com/you/explorer/gene/?gene_name=SUOX you can see your SUOX results. The common result for rs705703 is CC, though there's no indication that T causes any problems. The normal results for i5000977 and i5000976 are both AA.
    Heterozygous MTRR mutations don't have an impact, but if you have another +/- missense mutation, it could slow down the functioning of the gene a bit. The other missense mutations are listed at http://forums.phoenixrising.me/index.php?threads/interesting-mtrr-variations.24551/ and they're the underlined ones.
    Nothing really, but the "not genotyped" stuff on the Yasko list isn't particularly important anyhow.
     
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