I am wondering how you find out which are the risk alleles, or mutations that potentially cause disease. For instance I found out which genes to look for for Ehlers Danlos--in my raw data there are gobs of homozygous results, but I don't know how to tell which versions are the normal or the risk alleles. Mutations in the following can cause Ehlers–Danlos syndrome: Fibrous proteins: COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, and TNXB Enzymes: ADAMTS2, PLOD1, B4GALT7 Can someone help? On a steep learning curve with the genetic stuff. I currently have no less that 15 ribs out of place (super painful), so I'm thinking EDS right about now and would like to know more.