Hi all, Firstly can I say thanks to everyone on here. After years of being sent down the wrong path by the NHS this site has been a godsend. I've had my 23andme test done, and it's returned the following: Homozygous COMT V158M COMT H62H VDR Bsm MAO-A R297R Heterozygous MTHFR C677T MTRR A66G MTRR A664A BHMT-08 AHCY-01 AHCY-19 CBS C699T CBS A360A Would anyone be able to recommend a course of treatment? I've been suffering from gastritis / hypersensitive oesophagus for a few years (could be caused by the mutations above), as well as wired but tired / dark eyes etc, and don't seem to tolerate anything stimulating well at all, or sulphur foods. I'm a 39-year old fella. Any help much recommended!