I want to go further and say something bold (maybe) that I dont think CFS is an illness of the immune system. I think that instead neurotoxins that can overstimulate the CNS and immune system are left to circulate in the body for too long and that is what coses the haywire. I think instead that it is the liver that is either slowed down or unable to detox these class of compounds in the first place that coses CFS. I think that is it a reasonable explanation as to why viruses that are other while held down are able to become activated. I think that we should look to the liver to make sure that it is working properly, particularly its pathways of: Methylation, Sulphuration and Glucuronidation. Looking back, everytime my CFS was in remission it seemed to coincide with me taking large amounts of NAC, 2-4 gm. I am beginning to understand more why so.