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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. M

    Ponderings and speculations about purinergic signaling, in pursuit of a unified ME/CFS theory

    @Murph, I keep coming back to phosphorylation and low adenosine - so I'm back on the coffee :) I've been reading the old original potato apyrase experiments which talk about ATP and the way it competitively interacts with ADP, AMP and adenosine. I wondered if this is the metabolic trap Phair was...
  2. M

    Sticky Teeth sensation after exertion

    ALA helps.
  3. M

    Sticky Teeth sensation after exertion

    I have this too. it started happening after dentistry work where the trigeminal nerve was injected with anaesthetic. Burning mouth syndrome started not long after with TMJ activation/guarding - I could barely chew properly. The TMJ has settled down now. The dentist took a look at it last...
  4. M

    Ponderings and speculations about purinergic signaling, in pursuit of a unified ME/CFS theory

    NB - I'm a newb so I can't tag anyone in this post...or I just can't figure out how to do it!! Firstly, necessary8 can I please acknowledge your considerable skill in writing this thread – must have burnt a shedload of energy you don’t have. Thank you so very much – your information clarified...