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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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    Den Project Appeal for Gillian McCarthy, ME/MCS sufferer

    Organophosphates have long been recognized as one of the causes for ME/CFS symptoms and it definitely appears that those with MCS are much more likely to be those who have organophosphate and/or organochlorine poisoning. It does not however invalidate the viral and bacterial hypotheses for the...
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    A Good Night's Sleep? Not with ME/CFS

    I would like to add to your discussion regarding excitotoxicity in ME and FMS. EEG expert Frank Duffy discovered that ME patients experience a micro-seizure and he described alpha wave intrusion as being a major part of this finding. As you probably know, this is THE major finding in sleep...
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    Article: The Singh XMRV Patent The Next Cancer for XMRV? Prostate Cancer Results Validated/Progress

    Cannabis and ME/CFS I would like to note that cannabis is an NMDA/glutamate antagonist that buffers the glutamatergic excitotoxicity that occurs in ME/CFS. In essence, it is a neuroprotective chemical that is preventing further damage by excessive glutatmate in the CNS. It is no...
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    Article: Report From the OFFER 2010 Conference

    No cycles to break Pardon my scientific nerdiness (I know you were just taking in general but I thought I would point out a few things that might be helpful to understanding the physiology of these illnesses.) Although the cycles you mentioned may be the case for most "normal" folks or...