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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Search results

  1. O

    Hydroxy B12 and feeling foggy.

    Does hydroxyb12 not cross the BBB?
  2. O

    Pink Urine with Methyl- but not with Hydroxo-

    Were you taking these massive doses orally? Any B12 that isn't picked up by Intrinsic Factor will most likely be excreted in your feces/bile, not your urine. I think the pink urine is a better testament to injections or sublingual applications. Also I'm pretty sure the pink color has to do...
  3. O

    Pink Urine with Methyl- but not with Hydroxo-

    I received an injection of 1mg Methylcobalamin and soon after pissed beautiful pink urine. A week later I tried an equal injection of Hydroxocobalamin without any sign of excretion in my urine. Does this mean that HydroxyB12 is stored by the body (since it's the form found in food) while...
  4. O

    question about adenosylB12 & Glutathione?

    well it is a precursor to glutathione. L-cysteine is the rate limiting step so supplementing with that might have more of an impact on glutathione levels but I supplement with glutamine and glycine just in case since those 3 aminos make up glutathione. you can search the forums but there seems...
  5. O

    question about adenosylB12 & Glutathione?

    The impression that I got from scouring these forums was that an adequete healthy supply of glutathione in the body is necessary for methlytation and to protect active b12. THis makes alot of sense to me because glutathione is vital to health. BUT i have also read that excess glutathione may...
  6. O

    question about adenosylB12 & Glutathione?

    I understand that glutathione depletion/deficiency is actually a very bad thing in the face of CFS and undermethylation but I have read also that too much can deplete active methylb12 from the body. I dosed 500mcg sublingual methylb12 from jarrow and felt incredibly better in terms of mood...
  7. O

    question about adenosylB12 & Glutathione?

    I've been searching these forums to see if anyone knows if glutathione reacts with adenosylcobalamin to create glutathionylcobalamin in the same way that methylB12 does. I take glutathione precursors (L-Cysteine, Glycine, L-Glutamine), as well as Vitamin C and Alpha Lipoic Acid to boost...