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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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Search results

  1. U

    Different reports Genetic genie vs livewello

    Thank you Valentijn If so does it mean i can't tolerate methyl B12 well and should take hydroxy B12 instead? cause i have comt V158 +/- also and i rade that you need less methyl groups in this situation.
  2. U

    Different reports Genetic genie vs livewello

    Hello I ran my raw data in livewello and received different results for my VDR TAQ gene than i received in genetic genie. Livewello report didn't show any mutation in this gene. but genetic genie showed i am Homozygous for this gene VDR taq +/+. Now i am confused, i used to take methyl B12 for...
  3. U

    Very confused about metylation

    Hey I did the 23andme test a few months ago. I thought i have some MTHFR issues because of my depression and CFS. The results showed no MTHFR mutations, but some other mutations: COMT V158M +/- COMT H62H +/- VDR Taq +/+ MAO-A R297R +/+ MTR A2756G +/- MTRR K350A +/- CBS A360A +/- I started...
  4. U

    23andme results no MTHFR mutations (Help)

    Hey I have finally done the 23andme test. This quite surprised me cause i was sure i had some mthfr issues but i don't. I suffer from chronic fatigue and depression which antidepressants do nothing for it. I found out i have some mtr/mtrr issues which as i read this mutation needs lots of...
  5. U

    Need help analyzing 23andme results

    Hey I have finally done the 23andme test. This quite surprised me cause i was sure i had some mthfr issues but i don't. I suffer from chronic fatigue and depression which antidepressants do nothing for it. I found out i have some mtr/mtrr issues which as i read this mutation needs lots of...
  6. U

    Fatigue since starting methyl folate

    Hey I started taking methyl folate few weeks ago i take (6S)-5-Methyltetrahydrofolic acid Since starting it i am feeling much more fatigue than before. I take only 1 mg daily, could this fatigue be because of this small amount? Should i increase my dosage? and the fatigue will be gone. It...
  7. U

    Methyl B12 issues (OCD,irritability)

    Hey Freddd Thanks for the priceless info :) Yes anxiety was always part of my life. must of the time it's under control but when i reach stressful situation i begin to lose it. I saw a video about this problem which relates stress to MTHFR. If i start low and go slow do you think i will be...
  8. U

    Methyl B12 issues (OCD,irritability)

    Hey Thanks for your answer Critterina I tried once to take b complex with 400 mcg of L-5-MTHF but it also contained 400 mcg of methyl B12. Then i felt even worse my anxiety was off the roof.. I didn't try methylfolate by itself. I did try cyanoB12 when i took it i was also a little bit anxious...
  9. U

    Methyl B12 issues (OCD,irritability)

    Hey Thanks for your answers Critterina I tried once to take b complex with 400 mcg of L-5-MTHF but it also contained 400 mcg of methyl B12. Then i felt even worse my anxiety was off the roof.. I didn't try methylfolate by itself. I did try cyanoB12 when i took it i was also a little bit...
  10. U

    Methyl B12 issues (OCD,irritability)

    Hello Just wanted to start by saying this is very informative forum. I rade about Methyl B12 here and how it can help with some mental issues. So i decided to give it a try. i tried taking 500 mcg of methyl B12 (by douglas labs) but it made me feel very anxious and my ocd got worse i tried...