[QUOTE="[Please, if you have a friend with hematological issues (especially bleeding, bruising issues) and weird problems with sleep, or muscle pain and muscle fatigue issues, look it up.QUOTE]
I've had so many other SNPs on my plate to learn and address that I haven't been able to get back to this one.
The above users post triggered an email reminder to me about it....I've been dealing with serious methylation crap, 677t, mtrr, fast COMT, taq1a.....methyl,methyl,methyl I figured out lol. Then it was on to APOE 4, which I'm working on and now I've found the HLAB27 buried in Promethease which was missed by a lab 11 years ago that might have altered a, few outcomes.... but then again could have killed me if they'd treated me with an antifolate like methotrexate. This DNA raw data has been invaluable in my helping myself and now I have a doctor on board with me even if it is my psych...after I showed him the mechanism by which homomcysteine triggers apoptosis via allosteric NMDAr modulation....at that point his ears perked up and he look at the rest of the studies I'd brought....
ok that got off subject, but months ago I think I missed the part about "bruising issues". LOL, I used to be a football player in high school and it was the weirdest thing....just from the usual grabbing and pulling of arms that occur during a game come Monday morning, my biceps on both arms would be all colors of the rainbow to the point that I wore special padding there by my senior year. These "grabs" were nothing extraordinary that caused the bruising and the bruising was 100 percent painless....just yellow, green, orange, red, purple depending on which day of recovery, which takes about 7 days. I still have this to this day. ..just not as much activity to cause such things.
no abnormal bleeding times, as I work in a lab and frequently collect my own blood and can also do a few very basic clotting assays which have always been normal.
interested in others experiences with this. when I looked at the FB group I didn't see much info and group did not appear very active and, as I said have been very busy addressing these other issues, which I think I'm finally getting enough of a handle on (aside from scheduling a trip to a GI doc since the news of the HLAB7....already have inflammatory skin hyperplasia issues, a bit of uveitis, reactive arthritis and IBS issues off and on for ages that has finally become I guess chronic. sigh.
EDIT: quote fail but I don't care. on mobile. not gonna fix. :/