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"I think all the supplements I'm taking now are just bandaids" <---- This!
Note I left out the sleep part, since while important for sure, it alone will not likely fix the many symptoms you have discussed in your posts.
And yes what you describe about driving yourself on the computer is a dead NE giveaway. Fortunately it is a more benign stage. It can get much worse leading to big crashes once the adrenals cave. And no most chronic stimulation of NE release is from the ANS and is not sourced in the adrenals. This is a common misconception. You have to find why the NE rushes. Less sleep certainly tips it the wrong way but sleep alone won't get you out of it.
And the whole point of NE is ... the body compensating for severe or chronic fatigue unless of course a true fight of flight response. Look at it another way a person with a dysregulated constant immune system attack (autoimmune or infectious) is essentially in a long perpetual state of fight or flight. Your body when sick would love for you to do nothing, lay around all day, sleep and do zip. But that is not how life works. The problem is over time if not corrected the sensitivity of the demands for no stress or lot of rest get higher and higher and the penalties in terms of NE get worse and worse until a person crashes. By then the adrenals are kaput if things go far enough.
NE may correlate with other adrenal dysfunction. But 9 /10 times you have to look at the immune system. That is where the command override authority sits. The other 1/10 are endemic neurotransmitter imbalances.
Did pregnenolone help you ? Why were you on it? It is the mother hormone. If you are deplete I would forget the GABA / NMDA worries they would be circumstantial in comparison. But I also would not try to self-medicate it without a doctor guiding you. Way to many interconnections. As an aside, my wife is on pregnenolone along with progesterone and estradiol and all her hormones completely balanced out (well except for some Armour thyroid her whole family has issues with). I took her to my same doctor a couple of years ago. She was like totally cured of her imbalances in like 3 visits. I was both happy and ridiculously envious. Sigh.
It is ironic since I should have been powering down hours ago. I have a bad head cold starting. I should be trying to sleep. But I am all full of "fake" energy at the keyboard? Why? NE. I am at that stage where I am still building to the peak. I am not looking forward to Easter weekend. This NE reaction is how my body reacts to inflammation at this point in my life because I spent so much of it getting swarmed by inflammation and ultimately living on NE. It should not be like that. It now usually isn't given the meds I take. But ... yeah ... you see the conundrum, right?
Anyways, now bedtime.
@dbkita
Where are you located? Can you provide the name of your wife's doctor and possibly contact information (phone). You can email me direct or just provide the name and I will look it up. Thanks
gratiasalvi1@gmail.com