Anyone know where to get IMIG online or in UK?

[msf]

But as SOC pointed out, we aren't sure what 'ME' is yet, so if low IgG is present in a proportion of patients it seems reasonable to treat this, and leave the discussion about what is and what isn't ME for when we actually understand the etiology of the disease/s.

 

[Jonathan Edwards]

But as SOC pointed out, we aren't sure what 'ME' is yet, so if low IgG is present in a proportion of patients it seems reasonable to treat this, and leave the discussion about what is and what isn't ME for when we actually understand the etiology of the disease/s.

Absolutely, it should be treated according to the rationale used for hypogammaglobulinaemia. Very few PWME will fall into the category that is considered to need treatment. And if you want to treat for hypogammaglobulinaemia 5gm shots IM are a waste of time.

 

[sarah darwins]

Treating patients without evidence is not good enough for patients - particularly if it involves wasting vast amounts of money that could go into proper research into something that might work.

You're conflating two things and misrepresenting both. "Limited evidence" might be fair, but that might, as I said before, be good enough for some patients. "Not good enough" is your opinion. And as for the "vast sums of money" ... I'm not seeing any evidence that this is the case. A small number of patients paying really pretty modest amounts. Most patients are not doing it. I have contributed to charities and will continue to when I can.

I am afraid getting reputations with patients is all too easy - you just seem clever and attentive. I worked for someone like that when I started out. He had a huge private practice but in the end got kicked out of the university hospital for being a phoney.

"Nut picking" variant of the straw man fallacy. Won't do.

The reason progress was made was that charities set up by people with arthritis or with family with arthritis raised enough money to fund professorships and research units.

We can't do both?
And I'm not at all convinced that the comparison with arthritis decades ago is a valid one. The landscape is very different now. There are additional, very 21st century problems in the M.E. situation.

But have they? Or is it wishful thinking? I f the results followed a clear pattern that would show up in a trial. Trials can actualy show up results that a doctor would find impossible to detect if they were unbiased. Relying on 'clinical judgment' is something people did fifty years ago but should now be a thing of the past.

Really? Blimey. I hope they're not following that line in emergency rooms. Your line on this feels dogmatic.

You ask is it wishful thinking? Maybe. Maybe not. I'll make my own call on that in consultation with my doctor. You seem to be speculating about the doctors you accuse of speculating.

They are more or less applicable to everything, but the only way to change that is to fund research, not pour money down the drain because doctors think they know more than they can possibly do.

Again, can't we do both?
I'm pretty sure some of the doctors you're accusing of self-delusion have contributed to research and continue to do so. What's the problem with patients who are comfortable about it being prepared to play a part in empirical research? It's not one thing or the other. That's another fallacy, a false dilemma.

This is not a scientific position. It is an evidence position and that is quite different.

When I was falling asleep last night I remembered this thread and remembered writing that and thought "Wrong". I withdraw the characterisation.

That may be true but you are constructing a very complicated rational argument here!!

Er, yeah.

No it isn't Sarah, you are waving a red herring.

Is "red herring" a term for an analogy you don't like? Granted it was a flamboyant analogy but I don't think it's unjustified. I stand by it. You've disagreed. We should probably move on and stop discussing fish.

She was suggesting seeing a specialist who knows how to se Ig in the right patients and there ain't no such specialist because nobody knows that from experience (or if they do they should have published it) and nobody knows enough about how the disease works to know it from theory - which seemed to be more what SOC was implying.

That last part seems a bit unfair and a subjective interpretation of SOC's comments, but let's wait to see if SOC replies.

One point — it's my understanding that at least some of the me/cfs specialists have had trouble getting anything even considered for publication. That's one of the many reasons I don't we should be dogmatic about all this. We're as far as can be from an ideal world. No point arguing for approaches which belong there.

Q. I'm interested (genuinely, nothing to do with this back-and-forth). Have you talked at length to any of the me/cfs specialists who have been prescribing Ig?

ps. I hate these point-by-point responses, but you did it to me so I'm doing it back! One time only, though. I have a lot to get done this week before I go and throw vast amounts of money at a specialist (well, 90 euros this time, but I suppose it all adds up).

 

[barbc56]

One point — it's my understanding that at least some of the me/cfs specialists have had trouble getting anything even considered for publication.

Hmmm, could it have anything to do with the fact that a lot of these "experts, IMHO," are basically talking rubbish? That's in addition to the fact that there isn't a lot of money available for research.

Many of these experts are also making a bucketful of money out of these "treatments".

I don't think they're delibertly being charlatans. I think that they do believe what they are saying.

When we waste prescious resources, accept less than vigorous research, any treatment that may have a valid use gets further and further away as it gets sidetracked by the less than scientific treatments.

I am not saying there shouldn't be freedom of choice. This is simply my personal opinion.

Barb

 

[Marky90]

With regards to immunoglobulins..

I don`t know how it is in America and the U.K, but in Norway we have clear-cut remission-cases with IVIG, and even IMIG (however most who takes IMIG, only see a modest rise in form).

Based on this I am of the opinion that all ME-patients should be able to try IVIG 1 time, the effects seem to come pretty fast (one girl went from bedbound to 70-80 % of former functioning).

Worst case scenario, it doesnt work, but some ME-patients will regain their lives from IVIG. At least to some degree.

In the norwegian national guidelines for ME/CFS-physicians (2015), it has been emphasised that the patient should be able to try treatment, when this isnt unreasonable with regards to side effects, cost, scientifics studies etc.

Were trying to get going a double blind placebo, or open-label, - study on IMIG in Norway. But I think IVIG is whats reasonable to look into, as it might be the dosing that predicts effect (one theory is that self-antibodies die out faster when they have to compete for a FC-receptor which prolongs antibodies` halflive. So - the higher the dosing, the higher the effect). However as @Jonathan Edwards points out, nobody really have a clue. though it probably isnt unreasonable to expect that when rituximab causes long term-remissions by wiping out our antibodies, then something alike probably happens when patients get much better from IVIG.

I expect that the studies conducted on IVIG is incosistent due to slack use of criteria. We need a study with e.g. canada-criteria.

 

[PhoenixDown]

Treatment also involves stress reduction, toxin free food and drink and choline/vitamin C.

Do you believe in toxins yourself? Ben Goldacre doesn't believe in toxins. What kind of food contains these toxins?

 

[susank]

FWIW - there are Lyme (Bb) antibodies in IVIG.

Of course also antibodies to various viruses.
I am thinking these antibodies "neutralize" the antigens in our bodies - to some degree.

I downloaded a study on this from years ago. I am a computer dumb dumb and would not know how to post it here.
I could email the attachment to someone if they could post the pages here.

(I think I have emailed the attachment to some folks on this list before??!!)

 

[susank]

Here is a link to the abbreviated version:

http://www.ncbi.nlm.nih.gov/pubmed/11982967

Looks like the whole study - including tables showing the antibodies and amounts in batches is availabe online only to subscribers. (Wiley online library).

But again - I downloaded it years ago when the whole article was available online.

It seems to be the only one of its kind.

 

[mission impossible]

Hello everyone,

Thank you for your replies! I didn't mean to create such an intense debate, but I suppose it is a good thing.

I haven't been able to read all comments yet but I hope to do so and write my reply and viewpoint in about a week's time.

In the meanwhile thank you all for your time and input.

Tim

 

[mission impossible]

Thanks for your reply daffodil. I think 5ml shots work out at half a gram. As to whether following up rituximab with immunoglobulin or it is the immunoglobulin itself that produces a who knows but there is a link via Cort's treatment resource page that suggest that long term use of by rituximab can produce hypogammaglobulinaemia and should be followed up with immunoglobulins? http://forums.phoenixrising.me/inde...ximab-treatment—incidence-and-outcomes.30862/

@charles shepherd no I haven't had proper testing for Lyme Disease yet because the NHS says I have the rash therefore I have lyme and they have put me on two weeks doxycycline which will have treated it and therefore there's no need for any further testing end of of story, that is what I have been told by gp. However by following a link on Dr Sarah Myhill's website to Dr Armin Schwartzbach who is supposedly an expert on lyme and confections I have followed his advice to take a combination of antibiotics, Plaquenil and enzymes for 1 month then come off for one week and then do the necessary testing for lyme and coinfections to make sure I've got rid of it and then take it from there. So that's my current plan.

@ Jonathan Edwards and Charles Shepherd re Immunoglobulin "at the moment the evidence that it is of any use in ME is inconsistent" I am growing tired of hearing UK and CFS doctors calling studies inconsistent end of story as if it is all black and white done and dusted. We need to be looking at why these studies are inconsistent i.e. are some of the studies of poor quality? what was the diagnostic criteria used etc? I Note recently a top US government Agency saying that 99% of studies ME are of very poor quality I can't quite remember the exact wording or statistics but that's the gist of it. Also it seems to me that IG therapy has produced complete recovery in some very severe m e cases and that is very unusual indeed, so I think it needs further investigation.

So here it is:
Dr Nigel Speight between 1994 and 2001 had 7 severe cases of m.e /cfs (6 out of the 7 were tube fed so it sounds like they were very severe). 6 out of the 7 were given IM or IV immunoglobulin and 4 out of 7 made a FULL recovery. I think it goes without saying that complete recovery in very severe cases is very rare indeed and any severe cases where complete recovery occurs needs to be looked into and properly investigated. The first of those 6 given immunoglobulin was 2 years later playing rugby and climbing mountains now that is what I am talking about, when I mean complete recovery I mean complete recovery.

This study may have been small yes but the fact that it helped some very severe cases so hugely means it needs looking into again not forgotten about, because studies are "inconsistent" Also I would add (not just Ig) why not do studies on the severe and very severe cases if we did studies with just severe cases we might actually get some consistent results for a change! Why are we not doing this already? I don't understand, it's completely crazy!

The other area where I think a lot of ME and CFS doctors in the UK are getting it wrong is the risk reward ratio. As Dr Nigel Speight suggests, when everything else has been tried, and in severe cases as a last resort then that is a good time to try immunoglobulins. In a situation like this the risk of doing nothing is greater than the risk of trying the immunoglobulins, for the patient that is. In severe cases of m.e were all else has been tried there is a risk of (if long term illness) complications gradually rise and as in Ms it is the complications that end up killing the patient . in such a situation surely a patient should be able to sign something to take the risk off the doctor in order to try it, on the other hand the risk of doing nothing means the risk of dying from complications or possibly even committing suicide in rare cases.I n severe cases where the quality of life is zero and I mean zero: no social contact noTV no music, lots of pain no escape, etc, how long can you carry on like that in social isolation 20 years 30 years?A t some point you have to try things and take risks in such a situation. Here is the link of Dr Nigel Speight on YouTube entitled "exercise and ME/CFS" where he asks for studies to be done on rituximab and immunoglobulin and also speaks of some of the cases where he has used immunoglobulins in some very severe cases successfully. See this link at about the 20 minute mark:

I'm glad both you guys, Jonathan and Charles, are happy to say you don't really know and nobody really knows regrding IG in ME. That is refreshing to hear a doctor say and it is a good start at least.

As for the vast cost of Ig, at half a gram a week which is all I can afford for a 3 month trial say would cost about $100 a month I estimate so it isn't that expensive(if I've got that right). Also I do and have donated to ME research including including invest in ME, just thought I'd mention that as well..

SOC and marky90 you both make some very good points:
- Bad science is basing medical decisions about testing and treatment on the fallacy that because there is no established treatment for ME, that no ME patient has treatable conditions. Bad science is refusing to test and then declaring there is no problem because you didn't find one.
- I expect that the studies conducted on IVIG are inconsistent due to slack use of criteria. We need a study with e.g. canada-criteria.

A ll said and done from where I'm sitting I will gladly give a IG a try even if it is at a low dose because that's all I can afford I can't see how I can attend the clinic in Belgium in my state but you never know.So basically because of NICE guidelines then it looks like if I am to try it, I will probably be forced to do so on my own terms, as per usual, well done NICE... thanks very much for that one.

 

[mission impossible]

Jonathan has covered the various reasons why you are very unlikely to find a doctor here in the UK who would be willing to prescribe im immunoglobulin for ME/CFS

We are asked this question on a fairly regular basis and I am not aware of any UK doctor - NHS or private - who is now prescribing immunoglobulin for people with ME/CFS

And I really would not recommend trying to buy a product like this off the internet and then trying to sort out the administration yourself…….

And has your Lyme disease been diagnosed using a reputable laboratory test?

Thanks for your reply daffodil. I think 5ml shots work out at half a gram. As to whether following up rituximab with immunoglobulin or it is the immunoglobulin itself that produces a who knows but there is a link via Cort's treatment resource page that suggest that long term use of by rituximab can produce hypogammaglobulinaemia and should be followed up with immunoglobulins? http://forums.phoenixrising.me/inde...ximab-treatment—incidence-and-outcomes.30862/

@charles shepherd no I haven't had proper testing for Lyme Disease yet because the NHS says I have the rash therefore I have lyme and they have put me on two weeks doxycycline which will have treated it and therefore there's no need for any further testing end of of story, that is what I have been told by gp. However by following a link on Dr Sarah Myhill's website to Dr Armin Schwartzbach who is supposedly an expert on lyme and confections I have followed his advice to take a combination of antibiotics, Plaquenil and enzymes for 1 month then come off for one week and then do the necessary testing for lyme and coinfections to make sure I've got rid of it and then take it from there. So that's my current plan.

@ Jonathan Edwards and Charles Shepherd re Immunoglobulin "at the moment the evidence that it is of any use in ME is inconsistent" I am growing tired of hearing UK and CFS doctors calling studies inconsistent end of story as if it is all black and white done and dusted. We need to be looking at why these studies are inconsistent i.e. are some of the studies of poor quality? what was the diagnostic criteria used etc? I Note recently a top US government Agency saying that 99% of studies ME are of very poor quality I can't quite remember the exact wording or statistics but that's the gist of it. Also it seems to me that IG therapy has produced complete recovery in some very severe m e cases and that is very unusual indeed, so I think it needs further investigation.

So here it is:
Dr Nigel Speight between 1994 and 2001 had 7 severe cases of m.e /cfs (6 out of the 7 were tube fed so it sounds like they were very severe). 6 out of the 7 were given IM or IV immunoglobulin and 4 out of 7 made a FULL recovery. I think it goes without saying that complete recovery in very severe cases is very rare indeed and any severe cases where complete recovery occurs needs to be looked into and properly investigated. The first of those 6 given immunoglobulin was 2 years later playing rugby and climbing mountains now that is what I am talking about, when I mean complete recovery I mean complete recovery.

This study may have been small yes but the fact that it helped some very severe cases so hugely means it needs looking into again not forgotten about, because studies are "inconsistent" Also I would add (not just Ig) why not do studies on the severe and very severe cases if we did studies with just severe cases we might actually get some consistent results for a change! Why are we not doing this already? I don't understand, it's completely crazy!

The other area where I think a lot of ME and CFS doctors in the UK are getting it wrong is the risk reward ratio. As Dr Nigel Speight suggests, when everything else has been tried, and in severe cases as a last resort then that is a good time to try immunoglobulins. In a situation like this the risk of doing nothing is greater than the risk of trying the immunoglobulins, for the patient that is. In severe cases of m.e were all else has been tried there is a risk of (if long term illness) complications gradually rise and as in Ms it is the complications that end up killing the patient . in such a situation surely a patient should be able to sign something to take the risk off the doctor in order to try it, on the other hand the risk of doing nothing means the risk of dying from complications or possibly even committing suicide in rare cases.I n severe cases where the quality of life is zero and I mean zero: no social contact noTV no music, lots of pain no escape, etc, how long can you carry on like that in social isolation 20 years 30 years?A t some point you have to try things and take risks in such a situation. Here is the link of Dr Nigel Speight on YouTube entitled "exercise and ME/CFS" where he asks for studies to be done on rituximab and immunoglobulin and also speaks of some of the cases where he has used immunoglobulins in some very severe cases successfully. See this link at about the 20 minute mark:

I'm glad both you guys, Jonathan and Charles, are happy to say you don't really know and nobody really knows regrding IG in ME. That is refreshing to hear a doctor say and it is a good start at least.

As for the vast cost of Ig, at half a gram a week which is all I can afford for a 3 month trial say would cost about $100 a month I estimate so it isn't that expensive(if I've got that right). Also I do and have donated to ME research including including invest in ME, just thought I'd mention that as well..

SOC and marky90 you both make some very good points:
- Bad science is basing medical decisions about testing and treatment on the fallacy that because there is no established treatment for ME, that no ME patient has treatable conditions. Bad science is refusing to test and then declaring there is no problem because you didn't find one.
- I expect that the studies conducted on IVIG are inconsistent due to slack use of criteria. We need a study with e.g. canada-criteria.

A ll said and done from where I'm sitting I will gladly give a IG a try even if it is at a low dose because that's all I can afford I can't see how I can attend the clinic in Belgium in my state but you never know.So basically because of NICE guidelines then it looks like if I am to try it, I will probably be forced to do so on my own terms, as per usual, well done NICE... thanks very much for that one.

 

[susank]

Tim - do you have a doctor that will prescribe the Gamma? Have you researched the various brands and their costs? In the US IMIG per cc or gram - if you can even get it - is much more expensive than the brands that are used SubQ. So you might want to compare prices IMIG vs SCIG - weighing the costs per cc and per gram.
The SCIG/SubQ brands might cost less for you. SubQ is also less painful than IM!

 

[Hip]

I am tyying to find out where I can get the intramuscular immunoglobulin shots organised. I would like to do 1 or even half a gram weekly. I live ih the UK, can't seem to figure out where to get here.

I have just been doing some Googling for you, and found the following info, which may be a starting point for tracking down clinics where you can get intramuscular immunoglobulin injections in the UK.

It looks like the newer approach of subcutaneous immunoglobulin infusions is worth investigating also, as these can be self-administered by yourself in your own home (takes a couple of hours each time, and I believe is typically performed once a week in those who need regular immunoglobulin treatments).

There is a Phoenix Rising article on IVIG for ME/CFS here.

This webpage has some interesting comments about the cost and sources of IVIG:

IVIG [is] priced at $ 48 to $ 60 a gram (cost price of IVIg). A single infusion of IVIg may cost about $3000 for a child to $10,000 for adults. For a child the cost is lower as a small IVIg dose is used. If you have insurance you will see the cost of infusion may go to 100,000. KabaFusion sells IVIG from $65 a gram to $72 a gram.(USA prices 5/5/2015).

The cost of IVIg in India & Pakistan $46 a gram, lower prices are found in China where the manufacturer will see IVIg for $10- a gram. This price has doubled in the last year. A pharmacy in Bangladesh Dhaka sells the cheapest IVIg 5 dollars a bottle of Baygam made in Germany. At cidpusa.org we ordered and tested this IVIg was 100% authentic. (infusions were done in Dhaka testing in Lahore). FDA does not allow foreign IVIg into USA.

On the www.fertilityfriends.co.uk fertility forum, some women talk about IVIG for pregnancy purposes. On this thread on that forum, there is mention of getting an IVIG fertility treatment at the Lister Fertility Clinic in London.

By Googling, I found several other UK fertility clinics offering IVIG:

ARGC IVF Clinic London (it costs £1500 for 25 grams)
Independent Health and Flight Clinic London
New Life Clinic Epsom, Surrey (costs £2200)

Maybe you can approach these and ask about the possibility of intramuscular or subcutaneous immunoglobulin.



In this thread on www.fertilityfriends.co.uk, there is a list of various IVIG products (brand names) available in the UK, which I have copied below (I have re-ordered the list slightly and added weblinks to the supplying pharmaceutical companies) :

This is what we have listed as available to UK pharmacies at the moment - most fertility docs here used to use octagam until recently but its not available anymore. I don't know which one of the others is the most suitable but here is the full list:

Gammagard S/D® (Baxter)
Intravenous infusion, (providing protein 5% or 10%), net price 0.5 g (with diluent) = £20.05, 2.5 g (with diluent) = £100.25, 5 g (with diluent) = £200.50, 10 g (with diluent) = £401.00

Kiovig® (Baxter)
Intravenous infusion, human normal immunoglobulin (protein 10%), net price 1 g (10 mL) = £49.00, 2.5 g (25 mL) = £122.50, 5 g (50 mL) = £245.00, 10 g (100 mL) = £490.00, 20 g (200 mL) = £980.00,
Note Use Glucose 5% intravenous infusion, if dilution prior to administration is required

Gammaplex® (BPL)
Intravenous infusion, human normal immunoglobulin (protein 5%), net price 2.5 g (50 mL) = £85.00, 5 g (100 mL) = £170.00, 10 g (200 mL) = £340.00
Note Contains sorbitol 50 mg/mL; contra-indicated in patients with hereditary fructose intolerance

Vigam® (BPL)
Intravenous infusion, human normal immunoglobulin (protein 5%), net price 2.5 g (50 mL) = £95.00, 5 g (100 mL) = £190.00, 10 g (200 mL) = £380.00
Note Contains sucrose (see Renal impairment, above)

Intratect® (Biotest UK)
Intravenous infusion, human normal immunoglobulin (protein 5%), net price 1 g (20 mL) = £45.00, 2.5 g (50 mL) = £112.50, 5 g (100 mL) = £225.00, 10 g (200 mL) = £450.00,

Privigen® (CSL Behring)
Intravenous infusion, human normal immunoglobulin (protein 10%), net price 2.5 g (25 mL) = £135.00, 5 g (50 mL) = £270.00, 10 g (100 mL) = £540.00, 20 g (200 mL) = £1080.00
Note Contains L-proline; contra-indicated in patients with hyperprolinaemia

Self-Administered Subcutaneous Immunoglobulin Infusion (SCIG)

Some pharmaceutical companies supply immunoglobulin products for self-administered subcutaneous infusion (SCIG):

SUBCUVIA® (Baxter) — video showing SUBCUVIA self-administeration here.
Hizentra® (CSL Behring)
Gammanorm® (Octapharma)
Subgam® (BPL)



At the bottom of this NHS document about intravenous immunoglobulin, there is a list of additional sources of information. Possibly if you contacted these sources, they may be able to direct you to clinics which offer intramuscular or subcutaneous immunoglobulin.

 

[mission impossible]

Thanks for the advice susank.

Hip lots to look into there, you must have put quite a lot of time into researching that on my behalf so I am very brateful thanks. The fertility angle, I would not have thought about that, interesting.

1st step I will try and price it all up and see if feasable, 2nd step try and find someone to prescribe it. This may take me a while, I will let you know.

thanks, Tim

 

[mission impossible]

Tim - do you have a doctor that will prescribe the Gamma? Have you researched the various brands and their costs? In the US IMIG per cc or gram - if you can even get it - is much more expensive than the brands that are used SubQ. So you might want to compare prices IMIG vs SCIG - weighing the costs per cc and per gram.
The SCIG/SubQ brands might cost less for you. SubQ is also less painful than IM!

No I don't have a doctor to prescribe the gamma, and that is my problem

 

[susank]

Researching - found an old topic from this site - interesting:

http://phoenixrising.me/conferences...s-part-iv-the-clinical-trials-by-cort-johnson

Scroll down to the section about Dr. Tae Park - IV Gamma.

FWIW I have heard people say they felt better after small doses of Gamma.
I have felt it. When I changed brands - waited a few weeks between doses for the switchover - then infused one gram SubQ - I definitely felt better.
Because I have CVID I have to take higher doses. The higher doses - well I think they make me feel a bit worse.

If I did not have CVID - I would hope to do just a gram a week - or less.

Hard to believe that that small amount can make a difference - but somehow seems it does in some people.

 

[Hip]

I know some people with ME who have become significantly better after intravenous gammaglobulins.

Were these people who benefited from IVIG adults?

Hip lots to look into there, you must have put quite a lot of time into researching that on my behalf so I am very brateful thanks. The fertility angle, I would not have thought about that, interesting.

I hope it helps. I am kind of getting interested in IVIG myself, after reading this thread. I always thought that IVIG was only useful in cases of ME/CFS caused by parvovirus B19, but it seems that IVIG may be of more general benefit in ME/CFS.

I wonder if any research has been done to try to characterize the ME/CFS patients that do respond well to IVIG.

Dr Nigel Speight between 1994 and 2001 had 7 severe cases of m.e /cfs (6 out of the 7 were tube fed so it sounds like they were very severe). 6 out of the 7 were given IM or IV immunoglobulin and 4 out of 7 made a FULL recovery.

Great video of Dr Nigel Speight that you posted.

With Dr Speight being a pediatrician, I take it that these 4 out of the 6 ME/CFS patients who made a full recovery after getting IVIG / IMIG were all children. I wonder if children are more likely to achieve full recovery from these immunoglobulin treatments.

 

[Marky90]

Were these people who benefited from IVIG adults?

Yep! One young adult, and one in her thirthies.

 

[mission impossible]

Great video of Dr Nigel Speight that you posted.

With Dr Speight being a pediatrician, I take it that these 4 out of the 6 ME/CFS patients who made a full recovery after getting IVIG / IMIG were all children. I wonder if children are more likely to achieve full recovery from these immunoglobulin treatments.[/QUOTE]

Good point, I'm not sure how old they were, but the one girl Dr Nigel Speight spoke about in the video somewhere was working at the post office 2 years after the start of IG I think so she must have been in her late teens I guess.

 

[mission impossible]

If you click on this link from the John Richardson Research Centre advice for doctors where the talk about IG treatment(if the link does not work as it was problematic pasting it in then just google it and you should find it easily)


http://m.hfme.org/site/mobile?dm_path=/wrichardson

and then click on "myagic encephalomyelits advice for doctors" on page 9 it gives info on IG treatment and doses used ie half a gram weekly, I think this was used on all ME age groups not just children?