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Lyme Disease--Alzheimer's: Correlation

GcMAF Australia

Senior Member
Messages
1,027
The chief medical officer has a report on lyme which is on some of the Lyme sites.
All the Federal Mps have been informed of the situation.
most of the state health departments have been informed and some hospitals
There has been a call for a Federal enquiry into the matter.
a number of Lyme patients are looking for lawyers
 

GcMAF Australia

Senior Member
Messages
1,027
[quote="Lillybelle, post: 484643, member:

Sorry this link
http://www.actionlyme.org/ talking about "govt whoring for its corporate pimps" does not convince me of anything. There is no evidence I can see there.]
I know this site is a bit out there.
I am not involved in the site.
The lyme doctors have similar feelings but do not express it in these ways
 

Lillybelle

Senior Member
Messages
110
Location
Australia
It is hard to get funding for any Lyme studies.
the ignoring of lyme disease in australia is not helpful either
Agreed, I hear your frustration.;) I'm very sorry for those who have Lyme, especialy chronic Lyme it sounds unspeakably horrendous. And I do believe it exists and is under reported. I just think extreme statements dont' help the cause.
 

Little Bluestem

All Good Things Must Come to an End
Messages
4,930
I think as the 6th leading CAUSE of Death, Alzheimers is extremely prevalent and highly fatal.
I think that some of the people who die of other causes also have Alzheimers, thus using fatality under-counts it's prevalence.

I would guess that the study quoted by GcMAF about used presence of disease, not cause of death, as the inclusion criteria, since they got a result different from the previous study.
 

MeSci

ME/CFS since 1995; activity level 6?
Messages
8,231
Location
Cornwall, UK
http://www.lymedisease.org.au/wp-content/uploads/2010/11/TBDConferenceNotesProfJMiklossy.pdf
Karl McManus Foundation
Tick Borne Disease Conference


www.karlmcmanusfoundation.org.au
Spirochetal infections and Alzheimer’s disease
–Evidence for a causal relationship
Professor Judith Miklossy
*
The detection of B.Burgdorferi In AD had
a 14 times higher frequency in AD brains compared to the
brains of the controls

A correlation doesn't necessarily tell you direction of causation, or even whether there is a causal link.

A very notable example is that it has long been assumed by most scientists in the field that the beta-amyloid plaques in the brains of Alzheimer's sufferers are causal of disease/symptoms. Yet decades of research based on removing/reducing such plaques has not produced any clinical improvements (unlike in crassly-crude animal 'models').

There is at least one group of scientists who suspect that the plaques may in fact be a consequence of the disease, not a cause, and perhaps even protective.

The finding of high levels of an infectious organism in a disease can indicate that the sufferer is unable to combat such infections as well as healthy controls. It doesn't necessarily mean that the organism is causal.
 

GcMAF Australia

Senior Member
Messages
1,027
Good Science Shows the Lyme spirochete and Alzheimers is Analogous to the Syphilis spirochete and General Paresis.
April 27, 2014 at 5:03am
1 - Lyme Neuroborreliosis and Dementia. [J Alzheimers Dis. 2014] - PubMed - NCBI
".. Pure Lyme dementia exists and has a good outcome after antibiotics. It is advisable to do Lyme serology(blood test) in demented patients, and if serology is positive, to do cerebrospinal fluid analysis with AI. Neurodegenerative dementia associated with positive AI also exists, which may have been revealed by the involvement of Borrelia in the central nervous system."
http://www.ncbi.nlm.nih.gov/pubmed/24762944

2 - Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease.
"... The data indicate that Borrelia burgdorferi may persist in the brain and be associated with amyloid plaques in Alzheimer's disease. They suggest that these spirochetes, perhaps in an analogous fashion to Treponema pallidum(Syphilis), may contribute to dementia, cortical atrophy and amyloid deposition. ..."

Note: Spirochetes create amyloid plaques of the same type seen in Alzheimers patients. Biofilms are amyloid deposits.
http://www.ncbi.nlm.nih.gov/pubmed/15665404

3 - Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.

"... spirochetes were observed in the brain in more than 90% of Alzheimer's disease cases. ... The analysis of reviewed data following Koch's and Hill's postulates shows a probable causal relationship between neurospirochetosis and Alzheimer's disease. Persisting inflammation and amyloid deposition initiated and sustained by chronic spirochetal infection form together ..."
http://www.jneuroinflammation.com/content/8/1/90



4 - 1987 Jul - Concurrent neocortical borreliosis and Alzheimer's disease.
"Borrelia spirochetes were directly visualized in autopsy brain tissue from a patient with Alzheimer's disease and were cultured from cerebral cortex in artificial media. ..."

Note: They grew living spirochete bacteria from brain samples of patients who died from Alzheimers.
http://www.ncbi.nlm.nih.gov/pubmed/3297997


5 - Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes.
"...Morphological changes analogous to the amyloid deposits of Alzheimer's disease brain were observed following 2-8 weeks of exposure to the spirochetes. ... These observations indicate that, by exposure to bacteria or to their toxic products, host responses similar in nature to those observed in Alzheimer's disease may be induced."
http://www.ncbi.nlm.nih.gov/pubmed/15894409




6 - Chronic inflammation and amyloidogenesis in Alzheimer's disease -- role of Spirochetes.
"Alzheimer's disease is associated with dementia, brain atrophy and the aggregation and accumulation of a cortical(large part of the brain) amyloid-beta peptide. Chronic bacterial infections are frequently associated with amyloid deposition. It had been known from a century that the spirochete Treponema pallidum(Syphilis) can cause dementia in the atrophic form of general paresis(paralysis). It is noteworthy that the pathological hallmarks of this atrophic form are similar to those of Alzheimer's disease. Recent observations showed that bacteria, including spirochetes contain amyloidogenic proteins and also that amyloid deposition and tau phosphorylation can be induced in or in vivo(petri dish) following exposure to bacteria ..."
http://www.ncbi.nlm.nih.gov/pubmed/18487847





The medical industry simply ignores this research. There is an unspoken principle in medicine. "Minimize the nature of a chronic infectious disease wherever they can get away with it which includes denying the cause is from an infectious disease." The symptom relieving drugs and extended medical care for Alzheimer patients generates billions of dollars for the industry. Treating the cause could cure or dramatically improve this infectious disease. They would ultimately lose billions if these patients health improved. Spirochetal infections of the brain cause Alzheimers and Dementia. They include the Lyme spirochete, the Syphilis spirochete, and the Leptospira spirochete.
The industry will not voluntarily admit they are more certain of the causes of many diseases which they currently claim is unknown. After all, how many members of the public read peer-reviewed research? When doctors and some researchers attempt to publicize or treat patients based on research which threatens incomes, they get punished. Just watch "Under Our Skin" a documentary about Lyme. You will see how corrupt the medical industry is. That's why we are protesting at the Infectious Diseases Society of America in May at MAYDAY, we are working on a RICO charge against the guilty medical parties , we are mounting a class action lawsuit against the CDC, and more efforts are being made. The medical fraud surrounding Lyme disease is a provable crime based on the research and statements of the guilty parties.
A correlation doesn't necessarily tell you direction of causation, or even whether there is a causal link.

A very notable example is that it has long been assumed by most scientists in the field that the beta-amyloid plaques in the brains of Alzheimer's sufferers are causal of disease/symptoms. Yet decades of research based on removing/reducing such plaques has not produced any clinical improvements (unlike in crassly-crude animal 'models').

There is at least one group of scientists who suspect that the plaques may in fact be a consequence of the disease, not a cause, and perhaps even protective.

The finding of high levels of an infectious organism in a disease can indicate that the sufferer is unable to combat such infections as well as healthy controls. It doesn't necessarily mean that the organism is causal.
 

GcMAF Australia

Senior Member
Messages
1,027
http://www.spirochaetalalzheimersassociation.org/launchmtg.html
Inaugural Meeting of Spirochaetal Alzheimer's Association-London
some selected quotes
"
Even Dr. MacDonald's subsequent discovery that the Borrelia was causing miscarriages and killing infants was ignored.

In 1985, whilst attending a conference in Vienna, Dr. MacDonald heard European researchers refer to Tertiary or Third-stage Lyme Disease of the brain.
Dr. MacDonald relates how he began his investigations using monoclonal antibodies to detect Borrelia, later switching to DNA-based techniques such as the Polymerase Chain Reaction (PCR),
and most recently, Molecular Beacons - extremely accurate DNA probes.

On the screen we see distinct bands on a strip, relating to seven of ten Alzheimer brain specimens which were PCR-positive for Borrelia.

'DNA sequence analysis - this is the most precise identification technology available today
pcr1.png


By 2021, the UK is predicted to have one million dementia sufferers - most of them victims of Alzheimer's. Worldwide, the human toll is staggering, not to mention the potentially destabilising economic costs of round-the-clock care for millions of people. Dr. MacDonald has asked if mankind is prepared to widen the keyhole view of Lyme Disease. The question is, can we afford not to?
 

GcMAF Australia

Senior Member
Messages
1,027

GcMAF Australia

Senior Member
Messages
1,027
http://www.leadertelegram.com/news/front_page/article_094b09ec-2500-11e4-a854-0019bb2963f4.html


Disease-borne tick population studied in Eau Claire County; preliminary results troubling

Preliminary results of a study started in May show that about one-fourth of deer ticks collected at Lowes Creek and Big Falls county parks contain the bacteria that causes Lyme disease.

“It’s incredibly high,” said Brady Olson, a microbiologist with the Eau Claire City-County Health Department, as he observed results from ticks he had just run through a real-time polymerase chain reaction, or PCR, a laboratory technique used to magnify and detect tiny bits of bacterial DNA extracted from ticks and identify it as the culprit that causes Lyme disease.

Department staff chose the two Eau Claire County parks to collect ticks used in the study because of their popularity with outdoors enthusiasts, said Shane Sanderson, the Health Department’s environmental health director.

“I’m a little more concerned about places people use,” he said.

The three-year study is being paid for by a grant from the federal Centers for Disease Control and Prevention The study is occurring here because the Eau Claire area is a hot spot for tick-borne illnesses.

As part of the study, the CDC is attempting to determine whether Lyme disease is worsening in the Midwest because of a warming climate. Scientists hope to learn about seasonal variations in ticks and the percentage that carry the Lyme bacteria.

In addition to the study, the grant also paid for the real-time PCR process, which can be put to other uses, Sanderson said. For instance, department staff hopes to use it next summer to check for E. coli levels at beaches when they are closed because of high bacterial levels, he said.

Trolling for ticks

Since May, Health Department staff members and student volunteers have been conducting “tick drags” once per week at the two county parks, alternating parks each week. The process involves dragging a weighted 4-foot-by-4-foot piece of cloth through tall grass. Ticks that cling to the cloth are collected and plopped into containers of alcohol.

At the lab, Olson sorts ticks, placing them into separate categories to find the smaller “deer” or “black-legged” ticks that carry Lyme and other diseases. He runs them through the PCR process to determine whether the ticks contain the bacteria to transmit illnesses.

After finding plenty of ticks in May and June, the tick-dragging crew came up empty in July. That finding backs up the thought that ticks tend to be scarce in summer and more abundant in spring and fall.

“The study is still preliminary, but if patterns show ticks are uncommon in July, that might have health implications,” Sanderson said. “If you are planning a picnic, you might think of July.”