Having 8/9 positive and M4 even 7x increased (result 49 , range <7 ), others close, I tried only hurzapine A, with minor improvement, occassionally, sometimes I feel nothing.
From MCAS drugs (vit C, ranitidine, loratadine and quercetin, is what I tried so far) I have quite big benefit with my neurodevelopmental symptoms, brain fog etc, (hope i dont jinx it), as well as from antivirals (Valtrex).
CellTrend test is ELISA, and as
@paolo explained in one of his post problem could be that it's not only to outer surface proteins but also inner surface receptor proteiins. But I still dont see a reason why would I be making very high autoantibodies to inner surface proteins?! Does this matter so much? I still dont get when or do autoantibodies penetrate cells sometimes?!
I also have Sjogrens and since M3 is found in 90% Sjogrens patients maybe this is why I am so high positive. But I got ME from mom's side, she has it, while Sjogren's is from dad's side - my aunt.
I'd prefer if these autoantibodies are significant but I dont believe in this much.
It is discouraging that Rituximab doesnt even work for Sjogren's fatigue.
But this all reminds me of autism findings - I listened to Dr Theo on MCAS, mentioned they find autoantibodies to brain in 30% of autistic kids, and those also have MCAS issues , allergies.
So 30% similar to ME case.