joejack102
Senior Member
- Messages
- 133
It seems like there are two different types of "activated" folate: Metafolin® and Quatrefolic®. Has anybody tried both? Can anybody tell me the differences, if any, you noticed between them?
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For me, Quatrefolic had a stronger effect, but not positive. It seemed to raise my adrenaline or something.
I took it at night and got a racing heart beat and the feeling like having woke up from a nightmare.
Methylfolate doesn't have that effect.
I also read in some study, can't find it right now, that quatrefolic raises folate blood levels more than other forms.
No, sorry. Since they both get converted to 5MTHF, I think their effect would be similar?do you know if quatrefolic raises nitric oxide more than metafolin?
Folinic Acid contains 5-formyl THF. That is another folate form. It doesn't have a methyl group
Thank you for explaining this and I wish I had your depth of knowledge to understand it all! In my case, I am doing really well with Hydroxy B-12 and Folinic Acid but do not tolerate any of the Methyl forms.
is there any link between methyl intolerance and histamine problems that you know of?
ThankyouThank you for explaining this and I wish I had your depth of knowledge to understand it all! In my case, I am doing really well with Hydroxy B-12 and Folinic Acid but do not tolerate any of the Methyl forms.
If there is a theory on that, I don't know it. I think there is some theory on undermethylators with high histamine tolerating methyl supplements well? But that doesn't work out for me. I would be an undermethylator and although methylfolate isn't horrible for me, I don't tolerate it that well either.is there any link between methyl intolerance and histamine problems that you know of?
HydroxoB12 is also the B12 form I tolerate best and I take that a lot. How do you take your B12 (sublingual/capsule/..)?
If there is a theory on that, I don't know it.