AndyPR
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Read more at https://www.facebook.com/notes/simo...s-immune-activation-and-hunt/343163262805297/Mark Davis finds the strongest evidence yet for ME/CFS immune activation and hunts for the trigger.
This is one of the most significant findings since the results from the first rituximab trial.
Using a completely new, cutting-edge approach Stanford’s Professor Mark M Davis has produced the most dramatic evidence yet of immune activation in ME/CFS. At the recent OMF Stanford Symposium, he showed unpublished evidence that the immune activation in ME/CFS, in the form of activated T cells, is on a par with that seen in cancer, MS and infection. That's a much bigger effect than has been seen in ME/CFS cytokine studies where the changes are altogether more subtle.
Davis is already looking for the specific antigens (small proteins recognised by the immune system) that are triggering the immune activation, again using new technology. So far, he says he's found one candidate from the new work, but he wants to verify the findings before revealing more details. Identifying the offending antigen or antigens could potentially provide a target for drug treatments.
Davis is pretty new to the field of ME/CFS, but he is a researcher with a remarkable reputation: an immunologist and professor at Stanford whose work is widely quoted by other researchers.
Thanks for the write-up @Simon