Has this been discussed? I'm blown away with this turn of events.
https://www.healthrising.org/blog/2...ts-chronic-fatigue-fibromyalgia-autoimmunity/
https://www.healthrising.org/blog/2...ts-chronic-fatigue-fibromyalgia-autoimmunity/
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Has this been discussed? I'm blown away with this turn of events.
https://www.healthrising.org/blog/2...ts-chronic-fatigue-fibromyalgia-autoimmunity/
Systrom believes an autoimmune process that’s damaging autonomic nerves is probably running rampant in ME/CFS, FM and POTS patients. The skin is just the starting place;
...
A recent study suggests he may be right. That study found damage to the autonomic nerves regulating microcirculatory blood flow to the lungs in fibromyalgia. Every measure of lung functioning (carbon monoxide transfer factor, carbon monoxide diffusion capacity, alveolar capillary membrane volume and pulmonary capillary blood volume) was significantly reduced in fibromyalgia patients. Further analyses found that the reduction in lung diffusing capacity was probably due to a significant reduction in lung capillary volume; i.e. the microvascular volume of the FM patients’ lungs had declined.
The authors proposed that the receptors on the endothelial cells that cause FM patients’ blood vessels to dilate have been so overstimulated over time that they’re not responding to signals to dilate anymore. That leaves them constricted and results in reduced blood flow.
I'm with you, waiting for the less brain fogged brainiacs to digest this and tie it all together.Wow - really really interesting!! (sorry, that's all I can contribute right now )
Wikipedia states that it has been implicated in Gulf War Illness. Wikipediasounds really positive I wonder if the drug he's using Mestinon has been tested at Stanford
David Systrom's research interested might throw some light on your lung condition, @Gingergrrl. Autoantibodies causing constriction in blood vessels.
The authors proposed that the receptors on the endothelial cells that cause FM patients’ blood vessels to dilate have been so overstimulated over time that they’re not responding to signals to dilate anymore. That leaves them constricted and results in reduced blood flow.
> autoantibodies to acetylcholine... Where can one get this tested?
BTW, you have had good results on IVIG, right? How do you see its positive effects in the light of Systrom's findings?
Sorry, haven't researched IVIG yet, but recent tests showed that I had low IgA and IgM in addition to low levels of B lymphocytes.. Would these findings make me s candidate for an IVIG treatment? Anything else I should test?
Would these two things match with the findings of the study or be a different issue?
@Hip and others..would the ANS be permanently damaged? Or are there ways to improve it.."repair" it?
@Gingergrrl so uplifting to read about the improvements you have had already
Is using high dose IVIG against autoimmunity in general inspired by the RA protocol (Jonathan Edwards)?
I have had probably had several autoimmune attacks over the last 20 years; low B12 (parietal cells?), low thyroid (Hashimotos?), intense upper back pain (Becterev?), Lupus antibodies found.
It feels like I am "under attack" in so many parts of the body - maybe it is a "perfect storm" of autoimmune reactions?
Doctor's here know little and can't do much. The (very frustrating) Norwegian health care system "locks" you to use only one "assigned doctor" and if you want to see a specialist you have to be referred by "your doctor".
Which test would you recommend that I ask for? Cell trends?
Not to my knowledge; once the autoantibodies that are blocking the transmission of nerve signals are gone, normal functioning would likely resume.
Not to my knowledge; once the autoantibodies that are blocking the transmission of nerve signals are gone, normal functioning would likely resume.
has no connection to the RA autoimmune protocol
I have very low B-12 but just tested negative for Pernicious Anemia which included parietal cell antibodies so it's low for another reason. I've had Hashimoto's since 2013.
I do not have back pain and am not sure what Becterev means?
I am negative on Lupus autoantibodies but if you test positive for them, would they not treat you for that in Norway (since Lupus is usually recognized by all mainstream doctors)?!!!
Is it an option for you to have treatment at Kolibri?
Have you tested for H.Pylori? Might affect B12 uptake.
Did you take antibiotics in the past?
Became histamine intolerant (MCAS?).
Actually, I was referred to a specialist, but upon re-testing she found the antibodies to be too low for a Lupus diagnosis.
I would be interested to know if you hear from the two patients who went to Kolibri.
So, the Cell Trend is the most important one should test for? Other things you would recommend to test for to verify (prove) that I would benefit from IVIG and/or Rituximab treatment?
I believe I'm right in saying that Ron hasn't said this, he's said that it could be but that it also could be other things, nothing has been proven yet?Ron Davis reported that his filtering experiments suggest that the problematic factor in the blood that appears to be messing with energy production in his tests is an autoantibody.
Murph said:The treatment combines a small amount of peanut flour with a very high dose of the probiotic Lactobacillus rhamnosus.
This bacterium, commonly found in small doses in yoghurt, is a known immune system modulator – it calms the immune system's response to things it would normally react to, reducing the severity of allergic reactions.
Paired together, the probiotic mix encourages the immune system to gradually tolerate larger and larger doses of peanut flour.
"Probiotics are very potent immune-modulating agents to shift the way the immune system responds. This particular probiotic has been shown in other situations to support tolerance-like responses. It creates an environment for the immune system to respond differently," Professor Tang said