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Old snp to new snp changed variant?

Paralee

Senior Member
Messages
571
Location
USA
I was checking out an old snp and it changed to another snp so I checked it out and it shows a different variant. What do you do when this happens? Go with the new one? Thanks
 

Paralee

Senior Member
Messages
571
Location
USA
@Valentijn , it was from an old list from 23andme and it was in the list of '#Differences between user's SNP calls and the rCRS'.....'MT, rs41400048, 250, C, T, the C is mine and the T is the ancestral. I found the one it had been incorporated with rs1116836 but it has a different variant. I'm having trouble with all those old snps, the ones I've tried don't come up in 23andme any more.
Evidently the whole snp set up is going to change this year, I wonder what 23andme will do.
 
Messages
15,786
@Paralee - rs1116836 isn't the new version of the same SNP. It's on an entirely different chromosome. rs41400048 doesn't exist as an rs number anymore, but that SNP probably isn't problematic, since it's not on a gene.
 

Paralee

Senior Member
Messages
571
Location
USA
@Valentijn , evidently a lot were replaced, incorporated or deleted in Nov, 2015. I hope they didn't have info I needed, but the enormity of checking each snp is beyond me, anyway. At least I have a little headway with your program but it's still out of my league.
They are fixing to rename our snps, aren't they? I get the feeling when things are changed starting September, 2017 our rs #'s are going to change to other numbers because of advancements in identifying more genes, etc.
 
Messages
15,786
They are fixing to rename our snps, aren't they? I get the feeling when things are changed starting September, 2017 our rs #'s are going to change to other numbers because of advancements in identifying more genes, etc.
rs numbers are from dbSNP, so 23andMe can't change them. It's also unlikely that dbSNP will change any that aren't errors.