Jesse2233
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I just found out I have high TNF-a at 58 (reference range is 22). My IL-6 has normalized since starting IVIG, and INF-y has come down from 80 to 7 (reference range 5) but it seems IVIG is not touching TNF-a. My CRP and ESR are normal.
I'm considering a few next steps that I know are linked to to lowering TNF-a.
Is this logical or might high TNF-a not be causing my symptoms and in fact be a reaction to an infection or just a red herring. FWIW I no longer have any viral-like symptoms, just POTS, low stamina, brain fog, and a general shakiness / feeing of neurological overwhelm. I have no pain.
I know that Enbrel didn't work out well for Fluge and Mella's four patients. But I don't know if their initial TNF-a levels were high or if Humira was considered. I have read a smattering of anecdotal reports saying Humira helped CFS patients including one person who no longer bothers with doctors and is functionally recovered, but obviously the evidence is sparse.
I also know there are a lot of natural treatments for lowering TNF-a but I've already tried several, and I don't know how effective others would be.
Thanks
I'm considering a few next steps that I know are linked to to lowering TNF-a.
- Increasing LDN
- Trying Wellbutrin
- Trying Humira
Is this logical or might high TNF-a not be causing my symptoms and in fact be a reaction to an infection or just a red herring. FWIW I no longer have any viral-like symptoms, just POTS, low stamina, brain fog, and a general shakiness / feeing of neurological overwhelm. I have no pain.
I know that Enbrel didn't work out well for Fluge and Mella's four patients. But I don't know if their initial TNF-a levels were high or if Humira was considered. I have read a smattering of anecdotal reports saying Humira helped CFS patients including one person who no longer bothers with doctors and is functionally recovered, but obviously the evidence is sparse.
I also know there are a lot of natural treatments for lowering TNF-a but I've already tried several, and I don't know how effective others would be.
Thanks
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