- Messages
- 29
Hi everyone,
I'm new to this site and there's a ton I will need to learn over the next few years, but I since I responded very well to TMG supplement (3000 mg/ day) and I have some methylation mutations along with chronic fatigue syndrome, I figure I can get some improvement now whilst I spend some time learning more about how to optimize my health.
To give you a brief overview of my condition, I am a 27 year old male. I progressed into a chronic fatigue state about 5 years ago. I don't believe it was caused directly by an illness or infection, although I was often sick throughout my life. I knew something was wrong when I would work one day of manual labour (or a bodybuilding session at the gym) and be unable to work/ workout for the next week due to sore muscles. The fatigue hasn't lifted over the years. I've lived with it everyday and it's impacted my career/ relationships/ social life.
The CFS started around the time I was put on an SSRI for anxiety/ low-level to moderate depression. The SSRI really helped the moodiness and anxiety (life-changing actually) but it worsened my fatigue. I would often sleep 12 hours. Fast forward to 2015, on the advice of a really, really good psychologist, I sought an ADD-Inattentive type diagnosis and was officially diagnosed by a psychometrist and put on Adderall. The stimulant medication was, again, a life-changing moment for me, and it helps a lot with the ADD symptoms and SOME fatigue, but the core CFS is still there.
So two days ago, I tried the TMG supplement and was very surprised by my reaction. I not only experienced increased energy, but:
-My head felt clear, noticeable also on awakening
-I've been sleeping less hours and waking easier
-My life-long stuffy nose from allergies has never been clearer despite allergy shots + sprays (I can finally BREATHE)
-My foggy/ cloudy vision from the CFS (hard to explain) has cleared up and I can see facial expressions better as I go throughout my day, see farther and more clearly into the distance, and my accommodation (looking from one object to another) is immediate as opposed to delayed before the TMG ( i.e. if I were working on the computer and a colleague walked into the room, if I looked at him/her it would be foggy/ vaguely cloudy at first).
-Speech improvement. Clearer pronunciation. Speaking takes less effort and drains me less. This was a surprise. I've since learned that DMG/ TMG are helpful to facilitate speech in people with Autism.
-I also experienced a mild-moderate feeling of WELLNESS on the TMG - this is also hard to explain but it's more than just a lifting of fatigue. I take wellbutrin and Adderall and although they relieve fatigue, that icky, ill, yucky feeling in the head and body (like when you have a low-level flu) was still there. But the TMG kind of removes that ill feeling a little bit which was a big surprise and proved to me a good chunk of my symptoms are more than just psychological, but are also biological.
Anyways, before I delve into all the information here, I was wondering if somebody could help me get on the fast-track to recovery with some advice on supplementation. I will list my genetic mutations below and what I think (through the research I've done thus far) are the appropriate supplements to take for each:
MTHFR C677T AG +/- : methylfolate
MTRR A66G AG +/- & MTRR A664A AG +/- : b12 hydroxycobalamin (COMT V158M & VDR Taq both negative)
BHMT-02 CT +/- & BHMT-08 TT +/+ : sunflower lecithin
MAO A R297R TT +/+ : SSRI or 5-htp
VDR BSM TT +/+ : Vitamin D3
In addition to this, I will continue with the TMG and also add in a little Sam-e since I seem to really respond to that as well (when I tried it a couple years ago but stopped once I was diagnosed with ADD and wanted to have a pure trial of stimulant medication).
Is methylation supplementation as simple as taking the above supplements? Is there something I'm missing ? Is there a direction somebody could kindly point me in to take my improvement even further ?
I really appreciate any feedback. I thank you all in advance as I wouldn't have even heard of methylation without this forum and others like it!!
Best,
Pheenix997
I'm new to this site and there's a ton I will need to learn over the next few years, but I since I responded very well to TMG supplement (3000 mg/ day) and I have some methylation mutations along with chronic fatigue syndrome, I figure I can get some improvement now whilst I spend some time learning more about how to optimize my health.
To give you a brief overview of my condition, I am a 27 year old male. I progressed into a chronic fatigue state about 5 years ago. I don't believe it was caused directly by an illness or infection, although I was often sick throughout my life. I knew something was wrong when I would work one day of manual labour (or a bodybuilding session at the gym) and be unable to work/ workout for the next week due to sore muscles. The fatigue hasn't lifted over the years. I've lived with it everyday and it's impacted my career/ relationships/ social life.
The CFS started around the time I was put on an SSRI for anxiety/ low-level to moderate depression. The SSRI really helped the moodiness and anxiety (life-changing actually) but it worsened my fatigue. I would often sleep 12 hours. Fast forward to 2015, on the advice of a really, really good psychologist, I sought an ADD-Inattentive type diagnosis and was officially diagnosed by a psychometrist and put on Adderall. The stimulant medication was, again, a life-changing moment for me, and it helps a lot with the ADD symptoms and SOME fatigue, but the core CFS is still there.
So two days ago, I tried the TMG supplement and was very surprised by my reaction. I not only experienced increased energy, but:
-My head felt clear, noticeable also on awakening
-I've been sleeping less hours and waking easier
-My life-long stuffy nose from allergies has never been clearer despite allergy shots + sprays (I can finally BREATHE)
-My foggy/ cloudy vision from the CFS (hard to explain) has cleared up and I can see facial expressions better as I go throughout my day, see farther and more clearly into the distance, and my accommodation (looking from one object to another) is immediate as opposed to delayed before the TMG ( i.e. if I were working on the computer and a colleague walked into the room, if I looked at him/her it would be foggy/ vaguely cloudy at first).
-Speech improvement. Clearer pronunciation. Speaking takes less effort and drains me less. This was a surprise. I've since learned that DMG/ TMG are helpful to facilitate speech in people with Autism.
-I also experienced a mild-moderate feeling of WELLNESS on the TMG - this is also hard to explain but it's more than just a lifting of fatigue. I take wellbutrin and Adderall and although they relieve fatigue, that icky, ill, yucky feeling in the head and body (like when you have a low-level flu) was still there. But the TMG kind of removes that ill feeling a little bit which was a big surprise and proved to me a good chunk of my symptoms are more than just psychological, but are also biological.
Anyways, before I delve into all the information here, I was wondering if somebody could help me get on the fast-track to recovery with some advice on supplementation. I will list my genetic mutations below and what I think (through the research I've done thus far) are the appropriate supplements to take for each:
MTHFR C677T AG +/- : methylfolate
MTRR A66G AG +/- & MTRR A664A AG +/- : b12 hydroxycobalamin (COMT V158M & VDR Taq both negative)
BHMT-02 CT +/- & BHMT-08 TT +/+ : sunflower lecithin
MAO A R297R TT +/+ : SSRI or 5-htp
VDR BSM TT +/+ : Vitamin D3
In addition to this, I will continue with the TMG and also add in a little Sam-e since I seem to really respond to that as well (when I tried it a couple years ago but stopped once I was diagnosed with ADD and wanted to have a pure trial of stimulant medication).
Is methylation supplementation as simple as taking the above supplements? Is there something I'm missing ? Is there a direction somebody could kindly point me in to take my improvement even further ?
I really appreciate any feedback. I thank you all in advance as I wouldn't have even heard of methylation without this forum and others like it!!
Best,
Pheenix997