shannah
Senior Member
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Out of Canada:
Abstract
Fibromyalgia is a syndrome characterized by chronic widespread pain and associated with sleep disturbance, depression, fatigue and cognitive dysfunction. Polypharmacy is commonly used but supportive evidence is limited. Most fibromyalgia trials focus primarily on pain reduction with monotherapy. This trial compares a pregabalin-duloxetine combination to each monotherapy.
SUMMARY:
This double-blind randomized controlled trial demonstrates improved outcomes with a pregabalin-duloxetine combination over either single drug for fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/26982602
Abstract
Fibromyalgia is a syndrome characterized by chronic widespread pain and associated with sleep disturbance, depression, fatigue and cognitive dysfunction. Polypharmacy is commonly used but supportive evidence is limited. Most fibromyalgia trials focus primarily on pain reduction with monotherapy. This trial compares a pregabalin-duloxetine combination to each monotherapy.
SUMMARY:
This double-blind randomized controlled trial demonstrates improved outcomes with a pregabalin-duloxetine combination over either single drug for fibromyalgia.
http://www.ncbi.nlm.nih.gov/pubmed/26982602