Prof Shoenfeld: autoimmune syndrome induced by adjuvants

[natasa778]

Professor Yehuda Shoenfeld is the founder and head of the Zabludowicz Center for Autoimmune Diseases at the Sheba Medical Center, which is affiliated to the Sackler Faculty of Medicine at Tel-Aviv University, Israel. He is also the Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel-Aviv University. His clinical and scientific works focus on autoimmune and rheumatic diseases, and he has been the recipient of multiple awards, including a Life Contribution Prize in Internal Medicine in Israel, 2012.

In recent years, Professor Shoenfeld noted that four conditions: siliconosis, Gulf War syndrome (GWS), macrophagicmyofasciitis syndrome (MMF) and post-vaccination phenomena were linked with previous exposure to an adjuvant, and that the patients also presented with similar clinical symptoms. In 2011, this led Professor Shoenfeld to suggest these comparable conditions should be grouped under a common syndrome entitled ‘ASIA’, for ‘Autoimmune (Autoinflammatory) Syndrome Induced by Adjuvants’.

In this Q&A we talk to Professor Shoenfeld about ASIA, and discuss his recommendations regarding further research in the field.

What is ASIA?

ASIA is a new syndrome, which refers to autoimmune syndromes induced by adjuvants. It includes several conditions that are not fully characterized as autoimmune diseases like systemic lupus, rheumatoid arthritis or scleroderma, but that are induced by chronic stimulation of the immune system by substances which may react as adjuvants. This chronic stimulation leads to the emergence of these new signs and symptoms, which include fatigue, arthritis, myalgia, and neurological manifestations. ...

http://www.biomedcentral.com/1741-7015/11/118

 

[snowathlete]

Someone should ask him what he thinks of ME/CFS

 

[Thomas]

My family is Israeli and may have a conection to Dr. Shoenfeld. He is on my list of doctors to contact and may be a fresh break from the classic ME doctors...

 

[Snow Leopard]

CFS related publications from Shoenfeld:

Chronic Fatigue Syndrome: Characteristics and Possible Causes for its Pathogenesis
http://www.cfids-cab.org/cfs-inform/Reviewcfs/bassi.etal08.pdf

Chronic fatigue syndrome with autoantibodies — The result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant
http://www.cfsitalia.it/Documenti/ChronicFatigue_HBV_vaccine_silicone_implants.pdf

Infection, Vaccination, and Autoantibodies in Chronic Fatigue Syndrome, Cause or Coincidence?
http://www.cfids-cab.org/rc/Ortega-Hernandez-1.pdf

Infection and vaccination in chronic fatigue syndrome: Myth or reality?
http://www.cfids-cab.org/cfs-inform/Immunology/appel.etal07.pdf

Autoantibodies, Polymorphisms in the Serotonin Pathway, and Human Leukocyte Antigen Class II Alleles in Chronic Fatigue Syndrome
http://www.cfids-cab.org/rc/Ortega-Hernandez.pdf

 

[Hanna]

I was in contact with prof Schoenfeld 3 years ago, as I live in israel. Was very disapointed, he advised me to go for a consultation with one of his two assistants in Sheba Hospital. I was there twice to see Dr Nancy Agmon-levin at the Zabludowicz Center for Autoimmune Diseases at the Sheba Medical Center. She had a very poor understanding of the disease, dismissed the Ritux thing and prescribed antidepressants and a consultation with a neuro psychiater.

 

[Thomas]

Thanks Hanna. That's quite unfortunate - I was hoping he might be a fresh alternative but it sounds like a big let-down. He didn't do any tests on you to determine autoimmunity or what possible treatments might help?

 

[Hanna]

No anything. ME isn't recognized in Israel and CFS is not a priority! Sad.

 

[Legendrew]

I suspect this to simply be another factor that can induce a strong enough immune response which leads to rapid development of the autoimmune processes and cycles in people who are predisposed to the condition.

 

[Snow Leopard]

I suspect this to simply be another factor that can induce a strong enough immune response which leads to rapid development of the autoimmune processes and cycles in people who are predisposed to the condition.

That is my opinion too.

 

[morse27]

Asia syndrome is not ME/CFS illness. Verified by open medicine foundation and by Nancy klymas

 

[Thomas]

Asia syndrome is not ME/CFS illness. Verified by open medicine foundation and by Nancy klymas

When did they verify this, is their a reference or did they tell you?

 

[morse27]

its the response of open medicine foundation and Nancy klymas in 2013.more I have received by error the diagnose of Me since 2010 after a flu vaccine with squalene adjuvant.I tried rituxan for me/cfs .and the doctor of OMF said me I have not biomarker of all our patients with me/cfs! But other known in AzsIS syndrome of schoenfeld and in all gulf war illness veterans

 

[morse27]

rituxan cant be a drug for ASIA syndrome.schoenfeld gave me the IVIG therapy

 

[Thomas]

its the response of open medicine foundation and Nancy klymas in 2013.more I have received by error the diagnose of Me since 2010 after a flu vaccine with squalene adjuvant.I tried rituxan for me/cfs .and the doctor of OMF said me I have not biomarker of all our patients with me/cfs! But other known in AzsIS syndrome of schoenfeld and in all gulf war illness veterans

Thank you