I really like MitoQ and take it daily because it's supposed to all go into the mitochondria, but I suspect it doesn't really work quite like they thought. Or maybe it works better than they thought or than I expected.
Anyway, supposedly 95% of MitoQ goes into the mitochondria, whereas only 5-10% of ubiquinol gets there. At the dose they recommend (10mg daily) MitoQ smakes me too speedy even though I'm at least 80% recovered from my problems (maybe closer to 90% recovered, although there are still days), and seems to contribute to some anxiety. Coincidentally, I just tried a 10mg dose today after several months of 5mg/day, just to see what would happen. So that subjective assessment is still current.
My thought is that maybe we need more CoQ10 in other parts of the cell, too, and MitoQ is so effective on mitochondria we don't get it there. Or maybe I just don't know what I'm talking about.
Suffice it to say that ubiquinol is actually a "smoother" energy boost (for me, at least) at doses over 600mg/day. However, unless you're Donald Trump in a non-bankruptcy year
, really high dose ubiquinol is hard to afford because at those doses is somewhat pricier than MitoQ.
I compromise by taking 5mg MitoQ every day + 200mg ubiquinol. That seems to do me just fine. That's still somewhat pricey, but since I consider largish doses of some form of CoQ10 to be essential, I live with it. And at 5mg/day, MitoQ is a pretty good deal. I may go buy some of the discounted stuff. It's definitely effective, and has been part of my recovery, for sure.