ppodhajski
Senior Member
- Messages
- 243
- Location
- Chapel Hill, NC
I have been having an interesting time looking at the Solute Transporters (SLC) of all the 15 gene samples I have with people of varying levels of disease. I have noticed a trend, that the number of SLC gene SNPs that a persons has with a frequency of under 20% is correlated with health. Those with under 20 have very few health complaints. Those with 40 or more start showing signs of debilitating health. The sickest person I have genes for, a 26 year old female on disability for several degenerative diseases and mental health issues, has over 80 SLC SNPs under 20%!
It is acknowledged they play a role in health
http://www.ncbi.nlm.nih.gov/pubmed/23506860
"The field of transport biology has steadily grown over the past decade and is now recognized as playing an important role in manifestation and treatment of disease."
If you have you promethease report you can count these simply by searching for SLC, set the sort function to "Frequency", and increase the "Allow" number to 80. Then just scroll through and count.
I made a video of how to do this here:
If you want to check what your SLC gene SNPs might signal you can check what the the specific gene does here:
http://www.bioparadigms.org/slc/intro.htm
or
http://www.genenames.org/genefamilies/SLC
Here are my SNPs that are under 20%
SLC28A2 Sodium/nucleoside
SLC6A4 Serotonin
SLC6A1 GABA
SLC5A1 Sodium/Glucose
SLC23A2 Sodium/Ascorbate
SLC40A1 Iron
SLC2A9 Urate Fructose
SLC35F1 Drug Metabolite
SLC45A3 Transmembrane Lipid?
SLC4A1 Chloride/Bicarbonate
SLC25A27 Proton Leak (Thermoregulation)
SLC2A1 Glucose
SLCO1B1 organic anions
SLC23A2 Sodium/Ascorbate
SLC6A3 Dopamine
SLC2A2 Glucose
SLC16A10 Aromatic Acids
SLC1A2 Glutamate Aspratate
SLC8A1 Calcium
SLC6A2 Norepinepherine
SLC6A4 Serotonin
SLC45A2 May transport substances required for melanin biosynthesis
SLC6A4 Serotonin
SLC18A1 Biogenic Amines into Vascules
SLC6A4 Serotonin
SLC22A18 ?
SLC36A3 Proton-coupled amino acid transporter
SLC1A2 Glutamate Aspratate
SLC45A2 May transport substances required for melanin biosynthesis
SLC34A1 Phosphate
SLC16A6 Monocarboxylate Transporter
SLCO1B1 organic anions
SLC28A1 Sodium Nucleotide
SLC6A2 Norepinepherine
SLC9A9 May act in electroneutral exchange of protons for Na+ across membranes.
SLCO1B1 organic anions
SLC16A6 Monocarboxylate Transporter
SLC22A5 Carnitine
SLC18A2 Vesicluar Amine Transporter
SLC4A5 Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport,
SLC2A2 Glucose
SLC2A2 Glucose
SLC25A43 Transmembrane Lipid?
It is acknowledged they play a role in health
http://www.ncbi.nlm.nih.gov/pubmed/23506860
"The field of transport biology has steadily grown over the past decade and is now recognized as playing an important role in manifestation and treatment of disease."
If you have you promethease report you can count these simply by searching for SLC, set the sort function to "Frequency", and increase the "Allow" number to 80. Then just scroll through and count.
I made a video of how to do this here:
If you want to check what your SLC gene SNPs might signal you can check what the the specific gene does here:
http://www.bioparadigms.org/slc/intro.htm
or
http://www.genenames.org/genefamilies/SLC
Here are my SNPs that are under 20%
SLC28A2 Sodium/nucleoside
SLC6A4 Serotonin
SLC6A1 GABA
SLC5A1 Sodium/Glucose
SLC23A2 Sodium/Ascorbate
SLC40A1 Iron
SLC2A9 Urate Fructose
SLC35F1 Drug Metabolite
SLC45A3 Transmembrane Lipid?
SLC4A1 Chloride/Bicarbonate
SLC25A27 Proton Leak (Thermoregulation)
SLC2A1 Glucose
SLCO1B1 organic anions
SLC23A2 Sodium/Ascorbate
SLC6A3 Dopamine
SLC2A2 Glucose
SLC16A10 Aromatic Acids
SLC1A2 Glutamate Aspratate
SLC8A1 Calcium
SLC6A2 Norepinepherine
SLC6A4 Serotonin
SLC45A2 May transport substances required for melanin biosynthesis
SLC6A4 Serotonin
SLC18A1 Biogenic Amines into Vascules
SLC6A4 Serotonin
SLC22A18 ?
SLC36A3 Proton-coupled amino acid transporter
SLC1A2 Glutamate Aspratate
SLC45A2 May transport substances required for melanin biosynthesis
SLC34A1 Phosphate
SLC16A6 Monocarboxylate Transporter
SLCO1B1 organic anions
SLC28A1 Sodium Nucleotide
SLC6A2 Norepinepherine
SLC9A9 May act in electroneutral exchange of protons for Na+ across membranes.
SLCO1B1 organic anions
SLC16A6 Monocarboxylate Transporter
SLC22A5 Carnitine
SLC18A2 Vesicluar Amine Transporter
SLC4A5 Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport,
SLC2A2 Glucose
SLC2A2 Glucose
SLC25A43 Transmembrane Lipid?
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