This paper and Chris Exley's talk also lead me to think we might be able to help ourselves.
If we can reduce the aluminium burden in our bodies, we may reduce our immunological abnormalities,
In Chris Exley's talk he mentions that girls who have become ill with ME following HPV vaccine (which has an aluminium adjuvant) have tried eliminating it from the body by drinking a silicon rich mineral water. Silicic acid will attach to aluminium and be excreted via the kidneys. Chris Exley's team have shown that alzheimers patients excrete less urinary aluminium after 12 weeks of drinking 11/2 litres mineral water. The water must have a high concentration of silicic acid and in the UK the only brand is Volvic.
Why industry propaganda and political interference cannot disguise the inevitable role played by human exposure to aluminum in neurodegenerative diseases, including Alzheimer's disease.
Exley C1.
"In the late 1980s, my Ph.D. research demonstrated the amelioration of acute aluminum toxicity in fish by silicon (
35). The unique inorganic chemistry of the reaction of aluminum with silicic acid [Si(OH)4] the only biologically available form of silicon, has remained my life’s work and is now the subject of a possible therapy to facilitate the removal of aluminum from the human body (
36). This therapy is based upon the observation that drinking silicon-rich mineral waters increases the excretion of aluminum in urine (
37). Silicon in mineral water (and indeed most potable waters) is found mainly as silicic acid, which in the gut is immediately absorbed and enters the blood before being excreted in the urine via the kidney. Mirroring the urinary excretion of silicic acid is aluminum and this close relationship suggests that silicic acid in some way facilitates the excretion of aluminum via the kidney. The mechanism of action remains to be elucidated but it is thought to involve a pulse in silicic acid concentration in the blood, which facilitates the passage of low-molecular weight (<18 kDa) forms of aluminum across the glomeruli of the kidney. The facilitation might involve the formation of hydroxyaluminosilicates (HAS) as our most recent research on the speciation of aluminum in blood identified a non-equilibrium phase of aluminum hydroxide (
38), which is a necessary precursor to the formation of HAS. While we have demonstrated this effect of silicon-rich mineral waters in healthy and in diseased individuals of all ages there remain a number of unresolved issues in relation to the efficacy of this treatment as a long-term therapy to reduce the body burden of aluminum. We need to establish if there is a lower limit for the silicon content below which there is no concomitant removal of aluminum from the body. At present, we have set this limit at 30 mg/L “silica” (as usually written on bottles) or 14 mg/L (0.5 mM) as silicon (silicic acid). We also need to understand the volume of water, which should be drunk each day and whether or not this volume should be taken as many small aliquots or several large aliquots. Our default position at the moment is that a minimum of 1 L should be drunk each day and it should be taken as only a few aliquots. While the majority of individuals who begin to drink the mineral water, as recommended above, show immediate increases in their urinary excretion of aluminum we do not have excretion data beyond 7 weeks for healthy volunteers and we do not know how long it will take for excretion data to indicate statistically significant reductions in individual’s body burdens of aluminum. While it is important that we obtain such data our default position on this is that to achieve maximum protection against everyday human exposure to aluminum the consumption of a silicon-rich mineral water should become a normal part of an individual’s diet and lifestyle. In a small cohort of individuals with Alzheimer’s disease, we were able to demonstrate a statistically significant reduction in their body burdens of aluminum over 12 weeks of treatment while in their age and gender-matched control population the reductions in body burden of aluminum did not reach statistical significance in the same period (
39). We do not, of course, know if aluminum is being removed from all of the body, for example, if it is being purged from the brain. The assumption, which is as good as we can make at the moment, is that all body stores of aluminum will be in some sort of dynamic equilibrium with the blood and so the removal of aluminum from the blood via the kidney will drive the removal of aluminum from other tissues including the brain. Tentative support for the removal of aluminum from the brain comes from our recent study on Alzheimer’s disease where 3 out of 15 individuals with the disease showed clinically relevant improvements in cognitive performance by the end of the study (
39)
http://journal.frontiersin.org/article/10.3389/fneur.2014.00212/full
