Bob
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This came to my attention via Tom Kindlon on Twitter. Note that it's a 2014 paper. (Perhaps I shouldn't have placed this in the ME/CFS section of the forum, as it's a study of primary MS patients.)
It's not open-access.
[I'm not sure if they are testing these MS patients for ME symptoms or for chronic fatigue. The abstract says that "the subjects were screened for CFS/ME symptoms", but it doesn't say which criteria were used.]
If these MS patients experience the same type of post-exertional exacerbation, as seen in ME patients, then this study could demonstrate an interesting association between MS and ME. Edit: However, Fukuda criteria were used in the study, and Fukuda doesn't require post-exertional exacerbation.
Multiple Sclerosis/Chronic Fatigue Syndrome overlap: When two common disorders collide
Gaber, Tarek A.-Z.K. | Oo, Wah Wah | Ringrose, Hollie
Journal: NeuroRehabilitation, vol. 35, no. 3, 2014
DOI: 10.3233/NRE-141146
http://content.iospress.com/articles/neurorehabilitation/nre1146
It's not open-access.
[I'm not sure if they are testing these MS patients for ME symptoms or for chronic fatigue
If these MS patients experience the same type of post-exertional exacerbation, as seen in ME patients, then this study could demonstrate an interesting association between MS and ME. Edit: However, Fukuda criteria were used in the study, and Fukuda doesn't require post-exertional exacerbation.
Multiple Sclerosis/Chronic Fatigue Syndrome overlap: When two common disorders collide
Gaber, Tarek A.-Z.K. | Oo, Wah Wah | Ringrose, Hollie
Journal: NeuroRehabilitation, vol. 35, no. 3, 2014
DOI: 10.3233/NRE-141146
http://content.iospress.com/articles/neurorehabilitation/nre1146
Abstract: INTRODUCTION: Fatigue is a major cause of disability and handicap in Multiple Sclerosis (MS) patients. The management of this common problem is often difficult. Chronic Fatigue Syndrome (CFS/ME) is another common cause of fatigue which is prevalent in the same population of middle aged females commonly affected by MS. AIM: This report aims at examining the potential coexistence of MS and CFS/ME in the same patients. METHOD: This is a retrospective study examining a cohort of MS patients referred for rehabilitation. The subjects were screened for CFS/ME symptoms. RESULTS: Sixty-four MS patients (43 females) were screened for CFS/ME. Nine patients (14%) with a mean age 52 (SD 9.7) who were all females fulfilled the Fukuda criteria for diagnosis of CFS/ME. Their symptoms, including muscular and joint pain, malaise and recurrent headaches, were not explained by the pattern of their MS. DISCUSSION: MS and CFS/ME are two common conditions with increased prevalence in middle aged females. As the diagnosis of CFS/ME is clinical with no positive clinical signs or investigations; it can be made with difficulty in the presence of another clear explanation for the disabling fatigue. Our results suggest that the two conditions may co-exist. Considering CFS/ME as a potential co-morbidity may lead to more focused and appropriate management.
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