In 1979, Dr. Goldstein discovered that he could cure acute mononucleosis infections in 90% of his patients in one to two days by using Tagamet. The theory behind this can be found on page 196 of
Chronic Fatigue Syndrome Treatment: A Treatment Guide (well worth the $4 if you don't already have this book). You can also find this page online
here. Tagamet is also helpful in reducing ME/CFS symptoms in general for 20% of the people who take it (sometimes by quite a bit); you may be more likely than most people to benefit from it since your CFS seems to be connected with your EBV.
Despite the fact that Dr. Goldstein published a paper on this, and the results were duplicated elsewhere, this still has not been adopted as a standard treatment for mononucleosis, so your doctor may not be familiar with it. However, it is quite effective; people with refractive mononucleosis used to travel long distances just to have Dr. Goldstein give them Tagamet. It was available only by prescription back then; now, you can get it over-the-counter at any drugstore, and cheap generic forms (cimetidine) are available. Tagamet is effective against all herpes viruses. From
Life Extension Magazine:
While pharmaceutical companies promote expensive and only partially effective anti-viral drugs, there is evidence dating back more than 20 years that the drug cimetidine (sold over-the-counter as Tagamet) is highly effective in shortening the duration or preventing the outbreaks of herpes and shingles. The problem is that virtually no physicians are prescribing cimetidine to their herpes (or shingles) patients, despite persuasive findings in peer-reviewed scientific journals.
There's also a thread about Tagamet and ME/CFS
right here on PR.
Zantac (ranitidine) works similarly to Tagamet; both are H(2) antagonists. Zantac has the advantage that it has fewer side effects than Tagamet. However, Tagamet seems to work for more people than Zantac.