picante
Senior Member
- Messages
- 829
- Location
- Helena, MT USA
I wrote a concise intro to my illness here: http://forums.phoenixrising.me/index.php?threads/hi-everybody-i-love-this-forum.33471/
I've been following the guide that @ahmo put together, and doing lots of searches on PR. What a great resource! @Freddd, you have all my admiration for discovering the deadlock quartet. That was a major feat of the intellect.
My responses to the protocol so far:
Less frequent hypoglycemia and significant pain relief (lower back).
No adverse reactions whatsoever to methylfolate (hooray!).
Started on 1 tab mB12 (1000 mcg) and 1/4 tab AdB12 (750 mcg-- it's a 3000 mcg tab)
First response to mB12/AdB12: diarrhea the second morning (methylfolate deficiency!)
In a week, I titrated slowly up to 2.5 mg methylfolate per day (divided into four doses).
On day 5, I added in some K-gluconate powder because I was having neck spasms. This helped!
Days 5 & 6 my fatigue was worse, and I had an increase in myofascial pain (forearms). Starting T3 6 years ago had relieved this pain, so this was the return of an old symptom. So on a hunch, ...
On day 7, I added a second dose of mB12/AdB12 (1000 mcg/750 mcg). This helped the myofascial pain, but triggered more neck spasms and low back inflammation, so I increased potassium and methylfolate.
Meanwhile, I started to bleed around day 5. I'm 1 year post-menopause, and Lugol's iodine was what finally stopped my intermittent spotting a year ago at age 57. I tried deleting some of the newer supplements, with no effect. So I increased my dose of Lugol's, and that stopped the bleeding.
I didn't add in L-carnitine until day 14 (liquid, approx. 125 mcg) and it triggered more fatigue, diarrhea, and brain fog. All much improved with more methylfolate.
Currently I've titrated up to twice a day mB12 (1000 mcg) and AdB12 (1/2 tab = 1500 mcg). 4.5 mg of methylfolate per day (in 4-5 doses) and potassium as needed, usually totaling 1000+ mcg per day. Jarrow liquid L-carnitine 1/2 tsp. = 167mcg.
Questions:
1. Is there a recommended procedure to try and get the best ratio of mB12 / AdB12? I tried increasing AdB12 to 2250 mcg one day, but felt worse.
2. When should I try raising L-carnitine? (No anxiety so far.)
3. I'm having a lot of sluggish brain & lack of focus (scattered). Maybe raise mB12 or metafolin more before I try raising L-carnitine?
4. Neurological brightening: I haven't experienced that. Why not?
5. Is there a see-saw between methyl trap and partial methylation block? Am I experiencing it?
Thank you kindly to anyone who offers guidance!
Julie
I've been following the guide that @ahmo put together, and doing lots of searches on PR. What a great resource! @Freddd, you have all my admiration for discovering the deadlock quartet. That was a major feat of the intellect.
My responses to the protocol so far:
Less frequent hypoglycemia and significant pain relief (lower back).
No adverse reactions whatsoever to methylfolate (hooray!).
Started on 1 tab mB12 (1000 mcg) and 1/4 tab AdB12 (750 mcg-- it's a 3000 mcg tab)
First response to mB12/AdB12: diarrhea the second morning (methylfolate deficiency!)
In a week, I titrated slowly up to 2.5 mg methylfolate per day (divided into four doses).
On day 5, I added in some K-gluconate powder because I was having neck spasms. This helped!
Days 5 & 6 my fatigue was worse, and I had an increase in myofascial pain (forearms). Starting T3 6 years ago had relieved this pain, so this was the return of an old symptom. So on a hunch, ...
On day 7, I added a second dose of mB12/AdB12 (1000 mcg/750 mcg). This helped the myofascial pain, but triggered more neck spasms and low back inflammation, so I increased potassium and methylfolate.
Meanwhile, I started to bleed around day 5. I'm 1 year post-menopause, and Lugol's iodine was what finally stopped my intermittent spotting a year ago at age 57. I tried deleting some of the newer supplements, with no effect. So I increased my dose of Lugol's, and that stopped the bleeding.
I didn't add in L-carnitine until day 14 (liquid, approx. 125 mcg) and it triggered more fatigue, diarrhea, and brain fog. All much improved with more methylfolate.
Currently I've titrated up to twice a day mB12 (1000 mcg) and AdB12 (1/2 tab = 1500 mcg). 4.5 mg of methylfolate per day (in 4-5 doses) and potassium as needed, usually totaling 1000+ mcg per day. Jarrow liquid L-carnitine 1/2 tsp. = 167mcg.
Questions:
1. Is there a recommended procedure to try and get the best ratio of mB12 / AdB12? I tried increasing AdB12 to 2250 mcg one day, but felt worse.
2. When should I try raising L-carnitine? (No anxiety so far.)
3. I'm having a lot of sluggish brain & lack of focus (scattered). Maybe raise mB12 or metafolin more before I try raising L-carnitine?
4. Neurological brightening: I haven't experienced that. Why not?
5. Is there a see-saw between methyl trap and partial methylation block? Am I experiencing it?
Thank you kindly to anyone who offers guidance!
Julie