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querying raw data in 23andme

ebethc

Senior Member
Messages
1,901
Can anyone tell me what "VERSION" means in 23andme?

In the Raw Data section, you can query a gene or SNP... The results show a table with the headers:
GENE, POSITION, SNP, VERSION, <NAME>'S GENOTYPE

So, for a particular gene BHLHE41 (with 3 snps) I got these results:

snp rs4963955, versions C or T, ebethc's genotype TT
snp rs4963956, versions C or T, ebethc's genotype CC
snp rs1480037, versions C or T, ebethc's genotype CC

Is the VERSION listed the bad result(s)? are BOTH C & T bad?
 
Messages
15,786
C and T are the alleles (variations). Usually neither version has any impact, or just has a very small impact.

If you want to know if an allele can cause problems you need to look up the research regarding that SNP. http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs= is the best site I'm aware of. And typically a variation has to result in a missense mutation or a stop-gain (changes in the protein created) to have any real impact.