BTW, for me, pituitary glandular was extremely effective for insomnia. And now, as my methylation improves, I'm finally sleeping well, staying asleep, returning to sleep easily after wakening in the night, for the first time in my life.
Yeah I thought things were improving with my sleep a couple nights ago but then they regressed last night.
I've been having insomnia combined with anxiety at night for the past few months where I will literally lay in bed staring at the ceiling for at least an hour to 2 before finally falling asleep. I also sometimes get this really weird sensation where I'll start dozing off, but my body will almost fight me to stay awake and I'll jump as I'm drifting off, like it doesn't want to sleep. It's really strange...
So a few nights ago, I actually fell asleep pretty quickly and had decent sleep. Same thing the next night. But then last night, I fell asleep really easily at first, woke up to go to the bathroom after a couple hours, and then had like a 2 hour insomnia/anxiety session. So I had a whole 2 days of good sleep and now it looks like I'm back to where I was.
Jay1218, Freddd has mentioned a few times recently that taking too much vitamin b1, 2 or 3 can increase the need for folate. Are you taking a b complex with 100 mg of B1? If so it could be too much.
I am taking 8 mg folate, 10 mg AD B12, around 20 mg Mb12 sublingual and 1 mg Mb12 by injection.
Hi Pela,
The B-complex I'm taking is the Douglas Labs one. Only 50 mg B1, 20 mg B2, and 50 mg B3, and I just started that a few days ago. It seems to be low dose enough to where it wouldn't be interfering with anything.
HI Jay,
Did you ever clearly get methylation started? Have you tried both ALCAR and l-carnitine fumarate (separately) to see which works? If no startup then did you try SAM-e, TMG, Biotin, D-ribose, zinc, vit D, magnesium and a few other things that can deadlock methylation and ATP startup? Higher doses don't do any good at all if you are still missing deadlocking essentials.
Hi Freddd,
Yeah I do feel like I've definitely gotten it started, but something is certainly missing. Here's kinda how I started off to give you an idea:
I recently restarted methylation a couple weeks ago (I attempted it a couple months back and stopped because I wasn't tolerating it well. Maybe this was a bad move in hindsight, but I was stuck and didn't know what to do).
The first few days of restarting it, I did around 200 mcg folate. I definitely felt something (more energy, nausea got a little better, better focus and cognitive ability), then after a few days my symptoms came back. I kept upping the dose every few days: 400 mcg, then 800, 1600, and so on and now I'm up to like 14x 800 mcg pills per day.
At the beginning of the folate, I only had hydroxy B12 and I was doing 2,000-4,000 mcg per day. I stopped the hydroxy and added in methyl/adeno B12 about a week ago. I now have that up to about 12 mg adeno and 8 mg methyl B12. I go through periods of the day where I feel pretty good, but still a lot of rough patches.
I just ordered some carnitine fumarate so will get that going when it comes in. My b-complex that I just got has biotin in it and I've been doing d-ribose, zinc, vitamin d, magnesium, etc. for months now so I don't think it's those.
Haven't tried TMG or SAM-e yet because I was trying to take things one step at a time (same reason I didn't start carnitine right away).
Every time I've increased the folate, I've had a day or 2 where things start feeling better, but they quickly regress again around the 3rd day or so. That's what led me to believe I was in some sort of deficiency and had to just keep increasing until I was out of it. But now at 14x pills per day and with the proper B12's on board and still not feeling 100%, there's gotta be something else I'm missing too.
Should I add in the TMG and SAM-e right now with the carnitine, or should I do the carnitine first, see what happens, then add those afterwards? I was just trying to take it slow so I know what's working and there weren't too many variables.
Thanks.