Soundthealarm21
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There have been several genes I have wanted to look up, but I don't understand how to navigate the raw data. Does someone know how to find specific genes (ie PEX, HLA DRBQ, etc)?
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The dbSNP link is the most useful. It should take you to http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=rs1054480 . G is the most common allele - is your "CC" result a typo?@ Sea how do I know if a gene is mutated from the raw data.
ADAMTS2 178540975 rs1054480 A or G CC
Reference Links:
Entrez Gene
Google Scholar (Gene)
dbSNP Lookup GG
Google Scholar (SNP)
What does all this mean/???
Sorry My results are GGThe dbSNP link is the most useful. It should take you to http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=rs1054480 . G is the most common allele - is your "CC" result a typo?
No, they're always listed in alphabetical order by 23andMe. To see which one is rare, you need to go somewhere like dbSNP. And to see if an SNP is known to have any impact, you need to read the research. Sometimes there are useful summaries of the research for a SNP at snpedia.com .If under "versions" it gives a C and a T is the first one listed (the C in this case) the normal one and the second one (T in this case) the mutated version?
dbSNP reports some genes backward. If it says REV near the top, then those alleles are reported backwards, and they'll also report the genotype prevalence backward at the bottom of the page. That SNP says "C/T (REV)" near the top, hence is backwards and the alleles are really A/G.The dbSNP link is the most useful. It should take you to http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=rs1054480 . G is the most common allele - is your "CC" result a typo?
Sorry My results are GG
dbSNP genotype CC
If results are different from dbSNP genotype does that mean is mutated? I am trying to understand the raw data since all the interpretation is Gone, I only find sites to interpret the methilations and Detox but not the other Genes. I am wondering about EDS since I look mutated? Or maybe I just don't understand well yet.
It's easier to spot the heterozygous ones.
All that tells you is what your alleles are. To determine whether you have a mutation or not and whether it is of any significance or not you have to read about the snp at dbSnp and beyond.
Would you mind walking me trough it in this example??? I don't know how to translate that explanation to real example. So step by step once I am in dbSnp there is a lot of information but I don't see how to determain the mutation. When I read and reaserch the gene only says if the gene is mutated, does not explain for me how to know that or what values to compare to.