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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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That's a great tip re the timing Freddd (Potassium and MF).Hi Lefti,
I take 600mg with each of 2 meals and 300mg a couple of other times. As the potassium appears to hinder absorption of methylfolate, I take the methylfolate an hour before meals or before the potassium. I take folate an hour before bedtime and 300mg of potassium at bedtime. The methylfolate appears to double the serum halflife or thereabouts of the b12s. The b12 can be taken when convenient as it is absorbed mostly mucosally. Without excessive b1, b2 and/or b3 and without folic acid or folinic acid, the timing wasn't nearly as critical as when I was always on the edge of deficiency.
That's a great tip re the timing Freddd (Potassium and MF).Hi Lefti,
I take 600mg with each of 2 meals and 300mg a couple of other times. As the potassium appears to hinder absorption of methylfolate, I take the methylfolate an hour before meals or before the potassium. I take folate an hour before bedtime and 300mg of potassium at bedtime. The methylfolate appears to double the serum halflife or thereabouts of the b12s. The b12 can be taken when convenient as it is absorbed mostly mucosally. Without excessive b1, b2 and/or b3 and without folic acid or folinic acid, the timing wasn't nearly as critical as when I was always on the edge of deficiency.
Hi Freddd,
What is wrong with the Jarrow 1mg sublingual?
Hi Freddd
Is there an upper limit for methyl folate consumption. If I get spasms I take more potassium. I have this headache today and yesterday had itching and sort of like a allergy reaction. When do you take more methyl folate? Do any of these affect BP. Yesterday I went to the dr to get blood to test potassium. My bp the second number was 96, usually in 70s it could be because I was at doctors.
Lefti
Hi Freddd
How do you Relieve symptoms. Do you just keep Taking potassium. And folate?
Hi Freddd
So you take 3 99mg potassium at a time?
Does this irritate the stomach?
Thanks
Lefti,Hi Freddd
Is there an upper limit for methyl folate consumption. If I get spasms I take more pottasium. I have this headache today and yesterday had itching and sort of like a allergy reaction. When do you take more methyl folate? Do any of these affect BP. Yesterday I went to the dr to get blood to test pottasium. My bp the second number was 96, usally in 70s it could be because I was at doctors.
Lefti
Lefti,
Alex and I were discussing Potassium a few days ago. People with ME can have elevated serum potassium but low potassium in cells (research done in Australia). If you can get your doctor to test red cell potassium - that will be a better indicator. Do keep in touch with your GP if taking high doses of potassium though, it does have risks if serum potassium becomes high.
Bear in mind too that potassium and magnesium work together in Mitochondria and Mag can also be low in ME patients.
Red cell, or serum Potassium?Thanks.
I got a chem 7 done the other day. My pottasium. is 4.1. Yesterday I had nauseau that later turned into a headache. I took pottasium every few hours. I also took folate since I had spadms also. I was not sure my symptoms were from low pottasium or low folate. Today again I have some nauseau. Not sure how to proceed in a safe manner to releive syptoms
That's a hell of a good question and I think we would all love an answer to it Freddd. Until ME is diagnosed very quickly after first onset and biochem is tested at that point, I very much doubt we will have firm answers. As you indicate yourself multiple simple failures of Biochem can affect vast numbers of reactions.Mag is critical. Lack can bring B12 to a grinding halt. People with ME can have elevated serum potassium but low potassium in cells (research done in Australia)
The question I have, is that a result of the things leading to ME or a causal factor?
Red cell, or serum Potassium?
Where does that sit on the Labs 'normal range' ?
That's a hell of a good question and I think we would all love an answer to it Freddd. Until ME is diagnosed very quickly after first onset and biochem is tested at that point, I very much doubt we will have firm answers. As you indicate yourself multiple simple failures of Biochem can affect vast numbers of reactions.
Ultimately though, whatever caused the mess, those of us who have had ME for years decades are likely to have to take at least moderate action on multiple messes as well as fixing our own particular core problem more aggressively and longer term.
I found he combination of Potassium & Magnesium in Aspartate form worked best for me personally. In my case in an intensive six week course - BUT I did not have your Mercury Poisoning - you could be a whole different ball game.
Loss of Potassium would indicate AVP (rather than Aldosterone) might be deficient which would (ironically) further lower with reducing blood volume. What is your serum sodium like? Have you done any specific investigations into factors affecting cerebral blood flow?
I had a hell of a time myself some years ago with urination drinking 7 litres water daily on top of other fluids and having a tongue so dry it went hard (as in I could not bend it). I do know Amytriptiline can be awful for this, and raising ALCAR can help. I was bed (or couch) bound close to all of the time with it. I know if made me dreadfully ill, at that time I did not yet have a correct diagnosis (ME) hence proper investigations were not made.
Dr Christina Orr developed a protocol that (for some) is effective at restoring blood flow but it does involve a drug not all of us can take. Given the high rates of urination (sometimes) that you suffer the very high nutrient need and where you need to get them to, this issue of water metabolism seems downright critical to your personally.