thank you, really, but for example... enzymatic therapy b12 is 1mg for each tablet .. to obtain 200 MCG ho small i have to cut the tablet?????? half tablet is 500 mg 1/4 is 250 mg how can i obtain 200 MCG???
and about potassium...how much should i take? and just if i notice symptoms or it is better to take it in advantage?
Hi Josh,
To clarify one thing, with the sublingual use of the 1000mcg pill, held for 45-120 minutes typically 15-25% can be absorbed. A way to titrate to effect is to keep it under your lip until you are satisfied with the intensity, then chew and swallow. That immediately stops the absorption.
Another way is just break up the tablet into crumbs, take a crumb or two each hour until you have a satisfactiory amount of neurological brightening. That is the aiming point. MeCbl by itself may give startup. If you start with 200mcg of Metafolin, its enough to get methylation startup and then immediately folate insufficiency. Then you titrate, maybe 200mcg each hour until the folate deficiency symptoms start to turn around. 200mcg of Metafolin will make you miserable.
It can cause intense paradoxical folate deficiency symptoms, and at those low amounts you will likely be flipping in and out of methyltrap which is miserable. 1 1000mcg enzy and 1/4 a Anabol Dibencoplex capsule emptied along the lower lip and gum and held for 2 hours with any amount of Metafolin will usually start methylation in hours and cause a low potassium in 3 days and low folate in the same time. Many people need to titrate up to 1600-30,000mcg depending upon how much other folates they take and how poorly their body deals with them. The lower the dose the longer you keep your body in b12 and folate starvation mode. Some people keep the dose so low that they retrace the same territory every day, over and over and over, because they turn off healing whenever it starts.
There will be an intensification of neurology symptoms and senses and any of the hundreds of symptoms of these deficiencies start changing and it can be unpleasant. The low potassium is genuinely dangerous. The symptoms of both are below to help sort out what is happening.
Version 1.2 12/08/2013
Group 1 – Hypokalemia onset. Symptoms may appear with serum potassium as high as 4.3. May become dangerous if ignored. Considered “rare” with CyCbl (cyanocobalamin) it is very common with MeCbl (methylcobalamin) and AdoCbl (adenosylcobalamin) and less so with HyCbl (hydroxycobalamin).
There does not appear to be a clear order of onset. The order of onset varies widely from person to person but many appear consistent for each episode for any given person. There tend to be more and more intense symptoms as it gets worse. Some people have ended up in the ER because of not recognizing the symptoms.
IBS – Steady constipation, Nausea, Vomiting, Paralyzed Ileum,
Hard knots of muscle, Sudden muscle spasms when relaxed, Sudden muscle spasms when stretching , Sudden muscle spasms when kneeling, Sudden muscle spasms when reaching , Sudden muscle spasms when turning upper body to side, Tightening of muscles, spasms and excruciating pain in neck muscles, waking up screaming in pain from muscle spasms in legs. Muscle weakness
Abnormal heart rhythms (dysrhythmias), increased pulse rate, increased blood pressure
Emotional changes and/or instability, dermal or sub-dermal Itching, and if not treated potentially paralysis and death.
Group 2a - Both
IBS – Diarrhea alternating with constipation, IBS – Normal alternating with constipation
Group 2b – Either or both
Headache, Increased malaise, Fatigue
Group 3 - Induced and/or Paradoxical Folate deficiency or insufficiency
These symptoms appear in 2 forms generally, the milder symptoms that start with partial methylation block and the more severe symptoms that come on as partial methylation block gets worse or very quickly with methyltrap onset.
Edema - An additional thing I would like to mention. I would never have found it without 5 years of watching the onset of paradoxical folate insufficiency and trying to catch it earlier and earlier and to figure out what was causing it and to reverse it. For me the onset order goes back to the day of onset now with edema. I noticed that within 2 hours of taking sufficient Metafolin I would have a near immediate increase in urine output.
Old symptoms returning
Angular Cheilitis, Canker sores,
Skin rashes, increased acne, Skin peeling around fingernails, Skin cracking and peeling at fingertips,
Increased hypersensitive responses, Runny nose, Increased allergies, Increased Multiple Chemical Sensitivities, Increased asthma, rapidly increasing Generalized inflammation in body, Increased Inflammation pain in muscles, Increased Inflammation pain in joints, Achy muscles, Flu like symptoms
IBS – Steady diarrhea, IBS – Diarrhea alternating with normal, Stomach ache, Uneasy digestive tract,
Coated tongue, Depression, Less sociable, Impaired planning and logic, Brain fog, Low energy, Light headedness, Sluggishness, Increase irritability, Heart palpitations,.
Longer term, very serious
Loss of reflexes, Fevers, Forgetfulness, Confusion, Difficulty walking, Behavioral disorders, Dementia, Reduced sense of taste, bleeding easily
Group 4 - HyCbl onset, degraded MeCbl onset after photolytic breakdown.
Itchy bumps generally on scalp or face that develops to acne like lesions in a few days from start.
