outdamnspot
Senior Member
- Messages
- 924
due to my severe insomnia, I've been thinking about trying Mirtazapine .. I was in fact on it a few years ago at 30mg, but found it provoked a severe increase in anxiety; I'm not sure how the pharmakinetics change with dosing, but I believe lower doses are far more sedating, so wasn't sure if I'd have an issue ..
anyway, I was wondering if a) tolerance develops to the sedative effects and/or hangover, b) if there's cross-tolerance with antihistamines (50mg of Doxylamine is like a sugar pill at this point), and c) if there's a risk of next-day irritability (something I get with Doxylamine)?
the only other thing I haven't tried is Lyrica, but I hear it can cause rebound anxiety and that tolerance develops ..
thanks!
anyway, I was wondering if a) tolerance develops to the sedative effects and/or hangover, b) if there's cross-tolerance with antihistamines (50mg of Doxylamine is like a sugar pill at this point), and c) if there's a risk of next-day irritability (something I get with Doxylamine)?
the only other thing I haven't tried is Lyrica, but I hear it can cause rebound anxiety and that tolerance develops ..
thanks!