Journeyman
Senior Member
- Messages
- 193
As a person whose explored may different areas of medicine to try and understand their own shortcomings I've found a potentially interesting overlap in the genotype diet as espoused by Peter D'Adamo and what I've learned from genetic polymorphisms as it relates the more generalised study of methylation.
I first learnt about the genotype theory about mid 2012 after a relative of mine told me that Peter D'Adamo had advanced his previous theories on the blood type diet into this new more advanced system. I did the measurements per his book and identified myself as the 'teacher' genotype and adopted the 'diamond' foods.
Sure enough I was higher functioning and the irony is that many of the foods indicated as positive for my genotype (Peanuts, turkey, goat meat, cabbage, brussel sprouts) were foods I craved so it was all very positive. As I learnt more about orthomolecular medicine (a separate interest area) I branched out into studying methylation which led me onto this very exciting area of epigenetics were I then had my SNP's revealed via the 23& Me testing protocol.
I've found it very interesting (particularly the detox panel results) which showed I had heterozygous mutations as per the image that should be attached to this post.
PS - I've had great difficulty capturing a screenshot of the full panel such that it shows all the SNP's in the table but is still on the one page captured by the screenshot : that little block of red you see at the very bottom is the one SNP that couldn't be tested or detected for whatever reason: GSTP1: important?
Basically CYP2D6, CYP1B1 and CYP1A2. With (more importantly?) a homozygous mutation for CYP2C19*17
I found, after the helpful interpretation of these results courtesy Valentijn, that many of these enzymes fell under the P450 category which I recall being referenced in the D'Adamo literature. I also learnt after checking each of my affected SNP's that they collectively dealt with xenobiotic metabolism. It was fascinating the read that certain foods were known to increase the enzymes that I was left deficient in by virtue of my SNP's eg: cabbage and broccoli noting what D'Adamo indicated as being beneficial foods for my genetic type.
I also always had big problems with gynecomastia in spite of eating a diet geared towards minimising estrogens. It does seem to show that the teacher genotype which was worked out based on my relative limb measurements etc. has been proven correct by the genetic tests I've had done.
I'm interested to know if anyone else has found similar results between the genotype results obtained from the D'Adamo system and what has been indicated by their genetic tests which from what I can see paint the even more accurate/personalised picture...
I first learnt about the genotype theory about mid 2012 after a relative of mine told me that Peter D'Adamo had advanced his previous theories on the blood type diet into this new more advanced system. I did the measurements per his book and identified myself as the 'teacher' genotype and adopted the 'diamond' foods.
Sure enough I was higher functioning and the irony is that many of the foods indicated as positive for my genotype (Peanuts, turkey, goat meat, cabbage, brussel sprouts) were foods I craved so it was all very positive. As I learnt more about orthomolecular medicine (a separate interest area) I branched out into studying methylation which led me onto this very exciting area of epigenetics were I then had my SNP's revealed via the 23& Me testing protocol.
I've found it very interesting (particularly the detox panel results) which showed I had heterozygous mutations as per the image that should be attached to this post.
PS - I've had great difficulty capturing a screenshot of the full panel such that it shows all the SNP's in the table but is still on the one page captured by the screenshot : that little block of red you see at the very bottom is the one SNP that couldn't be tested or detected for whatever reason: GSTP1: important?
Basically CYP2D6, CYP1B1 and CYP1A2. With (more importantly?) a homozygous mutation for CYP2C19*17
I found, after the helpful interpretation of these results courtesy Valentijn, that many of these enzymes fell under the P450 category which I recall being referenced in the D'Adamo literature. I also learnt after checking each of my affected SNP's that they collectively dealt with xenobiotic metabolism. It was fascinating the read that certain foods were known to increase the enzymes that I was left deficient in by virtue of my SNP's eg: cabbage and broccoli noting what D'Adamo indicated as being beneficial foods for my genetic type.
I also always had big problems with gynecomastia in spite of eating a diet geared towards minimising estrogens. It does seem to show that the teacher genotype which was worked out based on my relative limb measurements etc. has been proven correct by the genetic tests I've had done.
I'm interested to know if anyone else has found similar results between the genotype results obtained from the D'Adamo system and what has been indicated by their genetic tests which from what I can see paint the even more accurate/personalised picture...