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Be aware of taking high B1 doses if you hava a SULFA ALLERGY. Thiamin, or B1 contains sulfa, (link below).
I have an extreme allergic reaction to sulfa, and started B1 at 100mg a day without a problem. When I increased to 300mg a day, I got the kind of extreme deep muscle pain and headache I associate with sulfa allergy. Just wanted to share this. This may explain what's going on with others who have a negative response with higher doses.
Be aware of taking high B1 doses if you hava a SULFA ALLERGY. Thiamin, or B1 contains sulfa, (link below).
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Also what forms of B1 are folks taking?
I need a contact email addy for yhe Italian researchers on the B1 paper
can anyone help?
Since benfotiamine is fat soluble, does it need to taken more than once/day?
That is what I am not sure about. If the body can store it and release it as needed, more frequent doses might not smooth it out.even if it doesn't, wouldn't dividing it smooth out your experience? I tend to divide everything...
Dose is what matters, I have not read of any who have divided it, but determining the beneficial amount comes first.
I started out with 1000mg's of B1. It helped a great deal for about 2 months. At about the 6th week I started to bump
it up adding 100mg's every few days reaching 1300. My logic was that I could tweek the amout and squeeze a little more out of the treatment. I crashed. I then reduced the dosage back to 1000, which didn't help. I believe it was a combination of the increased activity and my screwing around with the dose. Not sure but I believe the crash lasted about a month, 5 days ago I dropped the dose to 500. On the morning of the 3rd day l noticed I felt like I did when the 1000mg dose kicked in. The efficacy "window" seems to be narrow and may change over time. Even during my crash I was at a higher point, when comparing low points, than before I started B1. I have no doubt about the positive effect it has on me.